Jon J. Vermeire

University of California, San Francisco — United States

Immunology and Microbiology · Life Sciences

19h-index1.1kcitations32works0.02yr avg
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Research Topics

Parasites and Host Interactions(22), Parasite Biology and Host Interactions(19), Helminth infection and control(10), Macrophage Migration Inhibitory Factor(6), Research on Leishmaniasis Studies(3)

Publications32 total

Development and optimization of a high-throughput screening method utilizing Ancylostoma ceylanicum egg hatching to identify novel anthelmintics
PLoS ONE·2019· 19 citedOpen Access
S1 Table. IC50 values of compounds tested in a HTS screen for inhibition of hookworm egg hatching.
Figshare·2019Open Access
Hookworm egg toxicity HTS screen and HeLa toxicity Hitpick Results.xlsx
Figshare·2019Open Access
Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research
International Journal for Parasitology Drugs and Drug Resistance·2016· 29 citedOpen Access
Odanacatib, a Cathepsin K Cysteine Protease Inhibitor, Kills Hookworm In Vivo
Pharmaceuticals·2016· 7 citedOpen Access
In vitro Screening of Compounds against Laboratory and Field Isolates of Human Hookworm Reveals Quantitative Differences in Anthelmintic Susceptibility
American Journal of Tropical Medicine and Hygiene·2013· 8 citedOpen Access
Characterization of the phytochelatin synthase from the human parasitic nematode Ancylostoma ceylanicum
Molecular and Biochemical Parasitology·2013· 14 citedOpen Access
Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A
Chemistry & Biology·2013· 47 citedOpen Access
Frequency and intensity of exposure mediate resistance to experimental infection with the hookworm, Ancylostoma ceylanicum
Experimental Parasitology·2012· 7 citedOpen Access
Cure of Hookworm Infection with a Cysteine Protease Inhibitor
PLoS neglected tropical diseases·2012· 31 citedOpen Access
Oxadiazole 2-oxides are toxic to the human hookworm, Ancylostoma ceylanicum, however glutathione reductase is not the primary target
International Journal for Parasitology Drugs and Drug Resistance·2012· 10 citedOpen Access
A furoxan–amodiaquine hybrid as a potential therapeutic for three parasitic diseases
MedChemComm·2012· 22 citedOpen Access
Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors
Chemistry & Biology·2011· 35 cited
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
Proceedings of the National Academy of Sciences·2010· 195 cited
AV411 (Ibudilast) and AV1013 are non-competitive inhibitors of macrophage migration inhibitory factor: a novel induced-fit allosteric inhibition mechanism (133.11)
The Journal of Immunology·2010
CD4+ T cells mediate mucosal and systemic immune responses to experimental hookworm infection
Parasite Immunology·2010· 22 cited
Characterisation of a fatty acid and retinol binding protein orthologue from the hookworm Ancylostoma ceylanicum
International Journal for Parasitology·2009· 73 citedOpen Access
Transcriptome analysis of<i>Schistosoma mansoni</i>larval development using serial analysis of gene expression (SAGE)
Parasitology·2009· 34 cited
Developmental expression analysis and immunolocalization of a biogenic amine receptor in Schistosoma mansoni
Experimental Parasitology·2009· 43 cited
Orthologs of macrophage migration inhibitory factor from parasitic nematodes
Trends in Parasitology·2008· 90 citedOpen Access
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Frequent Co-authors

Michael Cappello(14), Timothy P. Yoshino(11), David L. Williams(9), Yoonsang Cho(6), Elias Lolis(6), Lin Leng(5), Richard Bucala(4), Xin Du(3), Richard D. Bungiro(3), Andrew S. Taft(3), Rebecca S. Treger(3), Anton Simeonov(3), Lisa M. Harrison(3), Conor R. Caffrey(3), Ganesha Rai(3), Laura Abriola(3), G.V. Crichlow(2), Michael E. Hodsdon(2), Matt Gross(2), F C Gaeta(2)