Raymond A. Morge

Analytical Services — United States

Medicine · Health Sciences

7h-index392citations16works0.02yr avg
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Research Topics

HIV/AIDS drug development and treatment(7), HIV Research and Treatment(4), Inflammatory mediators and NSAID effects(3), Chemical Synthesis and Reactions(3), Asymmetric Synthesis and Catalysis(2)

Publications16 total

(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes
Journal of Virology·1996· 37 citedOpen Access
Spectroscopic studies of delavirdine mesylate (U‐90,152T) a bis(heteroaryl)piperazine (BHAP) HIV reverse transcriptase inhibitor
Journal of Heterocyclic Chemistry·1996· 2 cited
Targeting Delavirdine/Atevirdine Resistant HIV-1:  Identification of (Alkylamino)piperidine-Containing Bis(heteroaryl)piperazines as Broad Spectrum HIV-1 Reverse Transcriptase Inhibitors
Journal of Medicinal Chemistry·1996· 57 citedOpen Access
ChemInform Abstract: Discovery, Synthesis, and Bioactivity of Bis(heteroaryl)piperazines. Part 1. A Novel Class of Non‐Nucleoside HIV‐1 Reverse Transcriptase Inhibitors.
ChemInform·1994· 3 cited
Discovery, Synthesis, and Bioactivity of Bis(heteroaryl)piperazines. 1. A Novel Class of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors
Journal of Medicinal Chemistry·1994· 90 cited
Second generation bisheteroarylpiperazine (BHAP) HIV-1 reverse transcriptasae inhibitors: Enhancement of antiviral activity and aqueous solubility via 5- and 6-substitution of the indole ring
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)·1993
Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships of novel substituted indole analogs and the identification of 1-[(5-methanesulfonamido-1H-indol-2-yl)carbonyl]-4-[3-[(1-methylethyl)amino]pyridinyl]piperazinemonomethanesulfonate (U-90152S), a second-generation clinical candidate
Journal of Medicinal Chemistry·1993· 123 citedOpen Access
ChemInform Abstract: Reaction of 2‐(Alkylsulfinyl)‐, 2‐(Arylsulfinyl)‐, and 2‐(Aralkylsulfinyl)benzimidazoles with Thiols: A Convenient Synthesis of Unsymmetrical Disulfides.
ChemInform·1988
Reaction of 2-(alkylsulfinyl)-, 2-(arylsulfinyl)-, and 2-(aralkylsulfinyl)benzimidazoles with thiols: a convenient synthesis of unsymmetrical disulfides
The Journal of Organic Chemistry·1987· 28 cited
ChemInform Abstract: TOTAL SYNTHESIS OF 3‐OXA‐4,5,6‐TRINOR‐3,7‐INTER‐M‐PHENYLENE PROSTAGLANDINS. 1. HOTOCHEMICAL APPROACH
Chemischer Informationsdienst·1978
ChemInform Abstract: FACILE RING CLEAVAGE OF PROSTAGLANDIN EPOXY KETONES
Chemischer Informationsdienst·1978
Total synthesis of 3-oxa-4,5,6-trinor-3,7-inter-m-phenylene prostaglandins. 1. Photochemical approach
The Journal of Organic Chemistry·1978· 26 cited
Facile ring cleavage of prostaglandin epoxy ketones
The Journal of Organic Chemistry·1978· 1 cited
ChemInform Abstract: THE OCCURRENCE OF 13,14‐DIHYDRO AND 13,14‐CIS‐UNSATURATED PROSTAGLANDINS IN THE CORAL, PLEXAURA HOMOMALLA. SYNTHESIS OF 13,14‐CIS‐PROSTAGLANDIN E2, 15‐ACETATE METHYL ESTER, AND THE 13,14‐CIS ANALOGS OF PROSTAGLANDIN F2α AN PROSTAGLANDIN F2β
Chemischer Informationsdienst·1977
The occurrence of 13,14-dihydro and 13,14-cis-unsaturated prostaglandins in the coral, Plexaura homomalla. Synthesis of 13,14-cis-prostaglandin E2, 15-acetate methyl ester, and the 13,14-cis analogs of prostaglandin F2.alpha. and prostaglandin F2.beta.
Journal of the American Chemical Society·1977· 23 citedOpen Access
A synthesis o crystalline thromboxane B2 from a derivative of prostaglandin F2α1
Tetrahedron Letters·1976· 2 cited

Frequent Co-authors

Carolyn Biles(6), Donna L. Romero(5), William P. Schneider(5), Irene W. Althaus(3), Fritz Reusser(3), W. Gary Tarpley(3), Mariano Busso(2), Lionel Resnick(2), Richard C. Thomas(2), Norman Berrios-Pena(2), Paul D. May(2), Paul D. Johnson(2), Robert A. Olmsted(2), Toni J. Poel(2), Laurice A. Kopta(2), Satish Kumar Sharma(2), Richard Voorman(2), David R. Graber(2), John C. Sih(2), Douglas R. Morton(2)