Jonathan Bones

University College Dublin — Ireland

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index4.8kcitations145works1.52yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(59), Protein purification and stability(56), Monoclonal and Polyclonal Antibodies Research(51), Glycosylation and Glycoproteins Research(34), Virus-based gene therapy research(15)

Publications145 total

Assessing Effects of Leachables in Single-Use Systems used in Cell Therapy Manufacture
2025Open Access
Investigation into Clearance of Organic Compounds from Biomanufacturing Process Streams during Ultrafiltration/Diafiltration
2025Open Access
Quantitative Host Cell Protein Analysis across Innovator Monoclonal Antibody-Based Protein Therapeutics using the Orbitrap Astral Mass Spectrometer
2025Open Access
Characterisation of small RNA-based therapeutics and their process impurities by fast and sensitive liquid chromatography high resolution mass spectrometry
Journal of Pharmaceutical and Biomedical Analysis·2025· 1 citedOpen Access
Characterisation of small RNA-based therapeutics and their process impurities by fast, sensitive, and reproducible liquid chromatography high resolution mass spectrometry
2025Open Access
Characterisation of small RNA-based therapeutics and their process impurities by fast, sensitive, and reproducible liquid chromatography high resolution mass spectrometry
2025Open Access
Understanding the clearance behaviour of elemental leachables during ultrafiltration/diafiltration from process streams
Journal of Pharmaceutical and Biomedical Analysis·2025· 1 citedOpen Access
IMPROVING CELL THERAPY MANUFACTURING ROBUSTNESS WITH REAL-TIME ANALYTICS
Cytotherapy·2025
Combination of hydrophilic interaction liquid chromatography and top-down mass spectrometry for characterisation of adeno-associated virus capsid proteins
Analytical and Bioanalytical Chemistry·2025· 1 citedOpen Access
Anion exchange chromatography coupled to mass spectrometry for deciphering the complexity of a highly glycosylated fusion protein (“protein HGF”)
Journal of Chromatography B·2025· 1 citedOpen Access
Detection of host cell microprotein impurities in antibody drug products
Nature Communications·2024· 6 citedOpen Access
Gonococcal Mimitope Vaccine Candidate Forms a Beta-Hairpin Turn and Binds Hydrophobically to a Therapeutic Monoclonal Antibody
JACS Au·2024· 3 citedOpen Access
Microfluidic capillary electrophoresis - mass spectrometry for rapid charge-variant and glycoform assessment of monoclonal antibody biosimilar candidates
Journal of Pharmaceutical and Biomedical Analysis·2024· 4 citedOpen Access
Implementation of a LC-MS based multi-attribute method (MAM) and intact multi-attribute method (iMAM) workflow for the characterisation of a GLP-Fc fusion protein
Analytical Biochemistry·2024· 7 citedOpen Access
Quantitative Analysis of Poloxamer 188 in Biotherapeutic Process Streams Using Liquid Chromatography–Triple-Quadrupole Mass Spectrometry
ACS Omega·2024· 1 citedOpen Access
Implementation of a LC-MS based multi-attribute method (MAM) and intact multi-attribute method (iMAM) workflow for the characterisation of a GLP-Fc fusion protein.
2024Open Access
A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency
International Journal of Molecular Sciences·2024· 2 citedOpen Access
Characterization of an IgG1 monoclonal antibody oxidation variants at intact, subunit and peptide levels by High Resolution Accurate Mass (HRAM) mass spectrometry
2024Open Access
Development of a Rapid Adeno-Associated Virus (AAV) Identity Testing Platform through Comprehensive Intact Mass Analysis of Full-Length AAV Capsid Proteins
Journal of Proteome Research·2023· 13 citedOpen Access
Rapid characterization of adeno-associated virus (AAV) capsid proteins using microchip ZipChip CE-MS
Analytical and Bioanalytical Chemistry·2023· 2 citedOpen Access
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Frequent Co-authors

Pauline M. Rudd(12), Sara Carillo(12), Stefan Mittermayr(8), Florian Füssl(7), Craig Jakes(6), Silvia Millán‐Martín(6), Ken Cook(5), Amy Farrell(5), Barry L. Karger(5), Brett Paull(4), Kai Scheffler(4), Niaobh O’Donoghue(3), Kevin V. Thomas(3), András Guttman(3), Anne Trappe(3), Margaret Doherty(3), Niaobh McLoughlin(3), Lisa Strasser(3), Ana Knežević(2), Olga Gornik(2)