Alessandro Cascioferro

Medicine · Health Sciences

17h-index1.4kcitations27works7.02yr avg
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Research Topics

Tuberculosis Research and Epidemiology(22), Mycobacterium research and diagnosis(14), Antibiotic Resistance in Bacteria(6), Bacteriophages and microbial interactions(4), Biochemical and Molecular Research(4)

Publications27 total

SuFEx-based antitubercular compound irreversibly inhibits Pks13
Nature·2025· 7 cited
Synthesis and structure–activity relationships of aryl fluorosulfate-based inhibitors as novel antitubercular agents
Bioorganic & Medicinal Chemistry Letters·2023· 7 citedOpen Access
Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: Molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response
Journal of Proteomics·2021· 9 cited
Proteome remodeling in the <i>Mycobacterium tuberculosis</i> PknG knockout: molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response
2021· 1 citedOpen Access
TCR density in early iNKT cell precursors regulates agonist selection and subset differentiation in mice
European Journal of Immunology·2019· 9 citedOpen Access
Author response for "TCR density in early iNKT cell precursors regulates agonist selection and subset differentiation in mice"
2019
Author response for "TCR density in early iNKT cell precursors regulates agonist selection and subset differentiation in mice"
2019
New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach
Journal of Proteomics·2018· 25 citedOpen Access
Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in <i>Mycobacterium smegmatis</i>
Journal of Medicinal Chemistry·2017· 8 cited
PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis
PLoS Pathogens·2017· 105 citedOpen Access
PE_PGRS33 Contributes to Mycobacterium tuberculosis Entry in Macrophages through Interaction with TLR2
PLoS ONE·2016· 73 citedOpen Access
pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence
Nature Microbiology·2016· 98 cited
Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis
Scientific Reports·2015· 46 citedOpen Access
<i>Mycobacterium Tuberculosis</i> Evolutionary Pathogenesis and its Putative Impact on Drug Development
Future Microbiology·2014· 34 cited
Mycobacterial Sigma Factors and Surface Biology
ASM Press eBooks·2014· 5 cited
Targeting Type VII/ESX Secretion Systems for Development of Novel Antimycobacterial Drugs
Current Pharmaceutical Design·2013· 20 cited
Analysis of SecA2-dependent substrates in<i>M</i><i>ycobacterium marinum</i>identifies protein kinase G (PknG) as a virulence effector
Cellular Microbiology·2013· 64 cited
Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 of<i>Mycobacterium tuberculosis</i>
Pathogens and Disease·2013· 41 citedOpen Access
The PPE Domain of PPE17 Is Responsible for Its Surface Localization and Can Be Used to Express Heterologous Proteins on the Mycobacterial Surface
PLoS ONE·2013· 28 citedOpen Access
Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis
Nature Genetics·2013· 293 citedOpen Access
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Frequent Co-authors

Riccardo Manganelli(12), Roland Brosch(9), Giovanni Delogu(7), Michela Sali(6), Giorgio Palù(6), Laleh Majlessi(4), Wafa Frigui(4), Giovanni Fadda(4), Fabien Le Chevalier(4), Marco Bellinzoni(4), María‐Natalia Lisa(4), Pedro M. Alzari(4), Antonella Zumbo(4), Alexandre Pawlik(3), Eva C. Boritsch(3), Wilbert Bitter(3), Raffaella Iantomasi(3), Ivana Palucci(3), Gabriele Di Sante(3), Francesco Ria(3)