Asterios S. Tsiftsoglou

Aristotle University of Thessaloniki — Greece

Medicine · Health Sciences

27h-index3.2kcitations117works1.52yr avg
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Research Topics

Erythrocyte Function and Pathophysiology(17), RNA modifications and cancer(13), Mitochondrial Function and Pathology(10), Hemoglobinopathies and Related Disorders(9), Acute Lymphoblastic Leukemia research(9)

Publications117 total

Multiple classes of human intracellular Heme-binding proteins with pathology-associated polymorphisms of heme coordinating residues
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2025· 1 citedOpen Access
Targeting mitochondrial bioenergetics by combination treatment with imatinib and dichloroacetate in human erythroleukemic K‑562 and colorectal HCT‑116 cancer cells
International Journal of Oncology·2024· 2 citedOpen Access
Conventional and Innovative Molecular Approaches Developed for Treating Hemoglobinopathies
Elsevier eBooks·2023
The Key Role of GSH in Keeping the Redox Balance in Mammalian Cells: Mechanisms and Significance of GSH in Detoxification via Formation of Conjugates
Antioxidants·2023· 180 citedOpen Access
Protein Transduction Domain-Mediated Delivery of Recombinant Proteins and In Vitro Transcribed mRNAs for Protein Replacement Therapy of Human Severe Genetic Mitochondrial Disorders: The Case of Sco2 Deficiency
Pharmaceutics·2023· 6 citedOpen Access
Glutathione–Hemin/Hematin Adduct Formation to Disintegrate Cytotoxic Oxidant Hemin/Hematin in Human K562 Cells and Red Blood Cells’ Hemolysates: Impact of Glutathione on the Hemolytic Disorders and Homeostasis
Antioxidants·2022· 13 citedOpen Access
Neural Differentiation of Human Dental Mesenchymal Stem Cells Induced by ATRA and UDP-4: A Comparative Study
Biomolecules·2022· 18 citedOpen Access
Hemin accumulation and identification of a heme‐binding protein clan in K562 cells by proteomic and computational analysis
Journal of Cellular Physiology·2021· 15 cited
Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders
Molecular Therapy — Nucleic Acids·2021· 31 citedOpen Access
Erythropoietin (EPO) as a Key Regulator of Erythropoiesis, Bone Remodeling and Endothelial Transdifferentiation of Multipotent Mesenchymal Stem Cells (MSCs): Implications in Regenerative Medicine
Cells·2021· 119 citedOpen Access
PTD-mediated delivery of α-globin chain into Κ-562 erythroleukemia cells and α-thalassemic (HBH) patients’ RBCs ex vivo in the frame of Protein Replacement Therapy
Journal of Biological Research - Thessaloniki·2021· 7 citedOpen Access
In vivo biodistribution study of TAT-L-Sco2 fusion protein, developed as protein therapeutic for mitochondrial disorders attributed to SCO2 mutations
Molecular Genetics and Metabolism Reports·2020· 13 citedOpen Access
Stem cell factor is implicated in microenvironmental interactions and cellular dynamics of chronic lymphocytic leukemia
Haematologica·2020· 7 citedOpen Access
Formation of novel N-acetylcysteine-hemin adducts abrogates hemin-induced cytotoxicity and suppresses the NRF2-driven stress response in human pro-erythroid K562 cells
European Journal of Pharmacology·2020· 15 cited
Activation of KEAP1/NRF2 stress signaling involved in the molecular basis of hemin-induced cytotoxicity in human pro-erythroid K562 cells
Biochemical Pharmacology·2020· 24 cited
PS1130 STEM CELL FACTOR IS IMPLICATED IN MICROENVIRONMENTAL INTERACTIONS AND CELLULAR DYNAMICS OF CHRONIC LYMPHOCYTIC LEUKEMIA
HemaSphere·2019Open Access
Production and Transduction of a Human Recombinant β-Globin Chain into Proerythroid K-562 Cells To Replace Missing Endogenous β-Globin
Molecular Pharmaceutics·2018· 9 cited
Erythropoietin (rhEPOa) promotes endothelial transdifferentiation of stem cells of the apical papilla (SCAP)
Archives of Oral Biology·2018· 18 cited
Angiogenic Potential and Secretome of Human Apical Papilla Mesenchymal Stem Cells in Various Stress Microenvironments
Stem Cells and Development·2015· 98 citedOpen Access
Genetic manipulation of RPS5 gene expression modulates the initiation of commitment of MEL cells to erythroid maturation: Implications in understanding ribosomopathies
International Journal of Oncology·2015· 12 citedOpen Access
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Frequent Co-authors

Ioannis S. Vizirianakis(12), Lefkothea C. Papadopoulou(9), Athina Bakopoulou(7), Pavlos Garefis(5), Gabriele Leyhausen(4), Petros Koidis(4), Werner Geurtsen(4), Ioannis S. Pappas(4), Sol Ruiz(4), David E. Housman(4), Joachim Volk(3), Sofia K. Georgiou‐Siafis(3), Alan C. Sartorelli(3), Christian K. Schneider(3), Stephen H. Robinson(3), James F. Gusella(3), Vladimir Volloch(3), Willie Wong(3), Anastasia S. Politou(3), Ioannis Bonovolias(3)