Andrea M. Sefler

Scientific Consulting Group — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index858citations26works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(9), Synthesis and Biological Evaluation(5), Glycosylation and Glycoproteins Research(3), Analytical Chemistry and Chromatography(3), Quinazolinone synthesis and applications(3)

Publications26 total

Application of CRAFT in two‐dimensional NMR data processing
Magnetic Resonance in Chemistry·2016· 26 cited
The disposition and metabolism of GW695634: A non-nucleoside reverse transcriptase inhibitor (NNRTi) for treatment of HIV/AIDS
Xenobiotica·2010· 7 cited
Tandem Michael‐Addition/Cyclization Synthesis and EGFR Kinase Inhibition Activity of Pyrido[2,3‐d]pyrimidin‐7(8H)‐ones.
ChemInform·2004
Tandem Michael‐addition/cyclization synthesis and EGFR kinase inhibition activity of pyrido[2,3‐<i>d</i>]pyrimidin‐7(8<i>H</i>)‐ones
Journal of Heterocyclic Chemistry·2004· 5 cited
The Role of NMR in the Analysis of Chemical Libraries
Elsevier eBooks·2004· 3 cited
Neuromuscular Blocking Activity and Therapeutic Potential of Mixed-Tetrahydroisoquinolinium Halofumarates and Halosuccinates in Rhesus Monkeys
Journal of Medicinal Chemistry·2003· 22 cited
Hepatocyte Nuclear Factor 4 Is a Transcription Factor that Constitutively Binds Fatty Acids
Structure·2002· 303 citedOpen Access
Spectroscopic Techniques for Optimizing Combinatorial Reactions on Solid Supports
2001
ChemInform Abstract: Stereocontrolled Synthesis of cis‐Dibenzoquinolizine Chlorofumarates: Curare‐Like Agents of Ultrashort Duration.
ChemInform·2001
An improved DEPT–HMQC sequence for high‐throughput NMR analysis
Magnetic Resonance in Chemistry·2001· 8 cited
Stereocontrolled Synthesis of<i>cis-</i>Dibenzoquinolizine Chlorofumarates:  Curare-Like Agents of Ultrashort Duration
The Journal of Organic Chemistry·2001· 29 cited
Using One- and Two-Dimensional NMR Techniques to Characterize Reaction Products Bound to Chiron SynPhase Crowns
Journal of Combinatorial Chemistry·2000· 14 cited
2,5-Dimethylfuran (DMFu):  An Internal Standard for the “Traceless” Quantitation of Unknown Samples via<sup>1</sup>H NMR
Journal of Combinatorial Chemistry·1999· 48 cited
CCDC 118547: Experimental Crystal Structure Determination
The Cambridge Structural Database·1999Open Access
Conformational Studies and Structure−Activity Analysis of Lissoclinamide 7 and Related Cyclopeptide Alkaloids
Journal of the American Chemical Society·1998· 103 cited
Solid-phase synthesis of hybrid thiazolidinedione-fatty acid PPARγ ligands
Bioorganic & Medicinal Chemistry Letters·1997· 12 cited
A Template for Stabilization of a Peptide α-Helix:  Synthesis and Evaluation of Conformational Effects by Circular Dichroism and NMR
Journal of the American Chemical Society·1997· 75 cited
Design, Synthesis, and Evaluation of a Depsipeptide Mimic of Tendamistat
The Journal of Organic Chemistry·1997· 42 cited
ChemInform Abstract: A Convenient Method for Determining Cyclic Peptide Conformation from 1D 1H NMR Information.
ChemInform·1996
A convenient method for determining cyclic peptide conformation from 1D <sup>1</sup>H‐NMR information
International journal of peptide & protein research·1996· 15 cited
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Frequent Co-authors

Paul A. Bartlett(5), James B. Thompson(5), Eric E. Boros(5), Tomi K. Sawyer(4), Timothy D. Spitzer(4), Samuel W. Gerritz(3), Wayne L. Cody(3), István Káldor(3), Paul L. Feldman(3), Robert A. Mook(3), John A. Ray(3), Vicente Sámano(3), Timothy M. Willson(2), Steven J. Geib(2), Marisa C. Kozlowski(2), John X. He(2), Hyacinth C. Akunne(2), Benjamin R. Travis(2), Gary D. Bowers(2), Randy D. Rutkowske(2)