Marika Ruponen

University of Eastern Finland — Finland

Biochemistry, Genetics and Molecular Biology · Life Sciences

35h-index4.6kcitations119works2.32yr avg
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Research Topics

RNA Interference and Gene Delivery(33), Virus-based gene therapy research(21), Advanced Drug Delivery Systems(21), Retinal Diseases and Treatments(20), Retinal Development and Disorders(20)

Publications119 total

Intravitreal Sustained Release of Dexamethasone from a Self-Healing Injectable Hydrogel: An In Vivo Safety and Release Study
Molecular Pharmaceutics·2025Open Access
Drug release and pharmacokinetics of intravitreal liposomal injections: a case study with cyclic guanosine monophosphate derivative
European Journal of Pharmaceutical Sciences·2025· 1 citedOpen Access
New insights on liposomal formulations based upon tear film lipids: A combined study of safety and ocular surface pharmacokinetics
European Journal of Pharmaceutical Sciences·2025· 1 citedOpen Access
From inserts to chips: microfluidic culture and 3D astrocyte co-culture drive functional and transcriptomic changes in hiPSC-derived endothelial cells
Fluids and Barriers of the CNS·2025Open Access
Thermoresponsive Hydrogels with Tunable Viscoelasticity for Extended Ocular Drug Delivery
Biomacromolecules·2025· 2 cited
In vitro biophysical and biological profiling of commercial lipid-based dry eye products
European Journal of Pharmaceutical Sciences·2025· 2 citedOpen Access
Melanin-Binding-Based Discovery of Topically Instilled Carbonic Anhydrase Inhibitors for Targeted Delivery and Prolonged Action in the Eye
Molecular Pharmaceutics·2025· 4 citedOpen Access
Mutated LRRK2 induces a reactive phenotype and alters migration in human iPSC-derived pericyte-like cells
Fluids and Barriers of the CNS·2024· 4 citedOpen Access
Human iPSC-derived pericyte-like cells carrying the LRRK2 mutation induce a reactive phenotype and alter migration
2024Open Access
PL3 CendR peptide shows specific uptake in cultured Y79 retinoblastoma cells with nucleolar accumulation
European Journal of Pharmaceutical Sciences·2024· 1 citedOpen Access
Comprehensive ocular and systemic pharmacokinetics of dexamethasone after subconjunctival and intravenous injections in rabbits
European Journal of Pharmaceutics and Biopharmaceutics·2024· 5 citedOpen Access
Corrigendum to “A technological comparison of freeze-dried poly-ɛ-caprolactone (PCL) and poly (lactic-co-glycolic acid) (PLGA) nanoparticles loaded with clozapine for nose-to-brain delivery” [J. Drug Deliv. Sci. Technol. 93 (March 2024), 105419]
Journal of Drug Delivery Science and Technology·2024
A technological comparison of freeze-dried poly-ɛ-caprolactone (PCL) and poly (lactic-co-glycolic acid) (PLGA) nanoparticles loaded with clozapine for nose-to-brain delivery
Journal of Drug Delivery Science and Technology·2024· 14 cited
Novel melanin‐binding carbonic anhydrase <scp>II</scp> inhibitor for long‐acting topical glaucoma treatment
Acta Ophthalmologica·2024
Novel anti‐evaporative lipid‐based formulation for dry eye disease treatment
Acta Ophthalmologica·2024
Early-Stage Development of an Anti-Evaporative Liposomal Formulation for the Potential Treatment of Dry Eyes
ACS Pharmacology & Translational Science·2023· 5 citedOpen Access
Quantitative intravitreal pharmacokinetics in mouse as a step towards inter-species translation
Experimental Eye Research·2023· 12 citedOpen Access
Intravitreal CendR peptides target laser-induced choroidal neovascularization sites in mice
Journal of Controlled Release·2023· 9 citedOpen Access
Development of Lyophilised Eudragit® Retard Nanoparticles for the Sustained Release of Clozapine via Intranasal Administration
Pharmaceutics·2023· 13 citedOpen Access
Comparison of barrier properties of outer blood-retinal barrier models – Human stem cell-based models as a novel tool for ocular drug discovery
European Journal of Pharmaceutics and Biopharmaceutics·2023· 3 cited
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Frequent Co-authors

Arto Urtti(34), Eva M. del Amo(13), Elisa Toropainen(11), Kati‐Sisko Vellonen(11), Mika Reinisalo(9), Veli‐Pekka Ranta(7), Seppo Auriola(7), Annika Valtari(6), Jari Koıstınaho(5), Jooseppi Puranen(5), Emma M. Heikkinen(4), Eva Ramsay(4), Tatu Lajunen(4), Heidi Kidron(4), Seppo Rönkkö(4), Paavo Honkakoski(4), Unni Tengvall(4), Katja A. Puttonen(4), Astrid Subrizi(3), Markku Tammi(3)