Muriel Metko

Mayo Clinic in Arizona — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

3h-index67citations8works9.72yr avg
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Research Topics

Virus-based gene therapy research(6), CAR-T cell therapy research(6), Immunotherapy and Immune Responses(5), T-cell and B-cell Immunology(1), SARS-CoV-2 and COVID-19 Research(1)

Publications8 total

T cell exhaustion in poorly immunogenic HCC is partially rescued by checkpoint blockade but suppressed by oncolytic virotherapy
Molecular Therapy·2025· 1 citedOpen Access
Exploiting viral infection/vaccination to focus high-affinity T cell populations into tumors using oncolytic viro-immunotherapy
Molecular Therapy·2025· 3 citedOpen Access
Cancer Immunotherapy Using AIRE Conditioning of the Tumor Epitopeome
2024· 1 citedOpen Access
Intranasal Prime–Boost with Spike Vectors Generates Antibody and T-Cell Responses at the Site of SARS-CoV-2 Infection
Vaccines·2024· 4 citedOpen Access
APOBEC3B expression in 293T viral producer cells drives mutations in chimeric antigen receptors and reduces CAR T cell efficacy
Molecular Therapy Oncology·2024· 3 citedOpen Access
Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response
Nature Communications·2024· 46 citedOpen Access
Chimerization of the Anti-Viral CD8+ T Cell Response with A Broad Anti-Tumor T Cell Response Reverses Inhibition of Checkpoint Blockade Therapy by Oncolytic Virotherapy
2023· 3 citedOpen Access
Trap and ambush therapy using sequential primary and tumor escape-selective oncolytic viruses
Molecular Therapy — Oncolytics·2023· 6 citedOpen Access

Frequent Co-authors

Jason M. Tonne(8), Jill Thompson(8), Richard G. Vile(8), Benjamin Kendall(6), Mason Webb(5), Thanich Sangsuwannukul(5), Rosa María Díaz(5), Madelyn Moore(4), Lewis R. Roberts(4), Jacob P. van Vloten(3), Laura Evgin(3), Mark A. McNiven(3), Satdarshan P. Monga(3), Mitesh J. Borad(3), Sheeba Irshad(3), Maria P. Chiriboga Yerovi(2), Michael R. Olin(2), Antonella Borgatti(2), Alan Melcher(2), Jack Swanson(2)