Iswarya Karapa Reddy

AstraZeneca (United States) — United States

Immunology and Microbiology · Life Sciences

4h-index47citations5works8.82yr avg

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Research Topics

Immune Cell Function and Interaction(4), CAR-T cell therapy research(4), T-cell and B-cell Immunology(3), Cancer Immunotherapy and Biomarkers(1), Lymphoma Diagnosis and Treatment(1)

Publications5 total

Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor

15 cited

Journal of Medicinal Chemistry·2025· 15 cited

Degradation of IKZF1 prevents epigenetic progression of T cell exhaustion in an antigen-specific assay

8 cited

Cell Reports Medicine·2024· 8 citedOpen Access

Degradation of IKAROS prevents epigenetic progression of T cell exhaustion in a novel antigen-specific assay

2 cited

2024· 2 citedOpen Access

Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors

10 cited

Journal of Medicinal Chemistry·2024· 10 citedOpen Access

Discovery of a Novel Benzodiazepine Series of Cbl-b Inhibitors for the Enhancement of Antitumor Immunity

12 cited

ACS Medicinal Chemistry Letters·2023· 12 citedOpen Access

Frequent Co-authors

Gayathri Bommakanti(5), Kathryn A. Giblin(3), Deanna A. Mele(3), Adelphe M. Mfuh(3), Kevin J. Robbins(3), Marianne Schimpl(3), Haoran Tang(3), Neil P. Grimster(3), Niresh Hariparsad(2), Samantha Jane Hughes(2), Meha Singh(2), Minwei Ye(2), Andrew X. Zhang(2), Jeffrey A. Boerth(2), Alex J. Chinn(2), Christina Chan(2), Erin Code(2), Andrea Gohlke(2), Catherine S. Hansel(2), Meizhong Jin(2)