Chao Zhang

University of Southern California — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

41h-index12.2kcitations113works6.62yr avg
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Research Topics

Melanoma and MAPK Pathways(18), Protein Structure and Dynamics(11), Click Chemistry and Applications(11), Computational Drug Discovery Methods(10), Fungal and yeast genetics research(9)

Publications113 total

RAF inhibitors activate the integrated stress response by direct activation of GCN2
Nature Communications·2025Open Access
Targeting CTP synthetase 1 to restore interferon induction and impede nucleotide synthesis in SARS-CoV-2 infection
mBio·2025· 1 citedOpen Access
Access to 2,2‐Halofluorobicyclo[1.1.1] Pentanes via Non Ozone‐Depleting Ethyl Dihalofluoroacetate
Advanced Synthesis & Catalysis·2025· 10 citedOpen Access
Smart detection of subsurface anomalies: Concept, validation and applications
Tunnelling and Underground Space Technology·2024· 4 cited
Mono- and Difluoromethylation of 3(2<i>H</i>)-Pyridazinones
Organic Letters·2024· 5 cited
Macrocycles and macrocyclization in anticancer drug discovery: Important pieces of the puzzle
European Journal of Medicinal Chemistry·2024· 32 cited
Design, Synthesis, and Preliminary Anti-tumor Activity Studies of Novel 1,2-Disubstituted Hydrazines
Chinese Journal of Organic Chemistry·2024· 1 cited
Design, Synthesis, and Biological Evaluation of Resorcinol-Based Novel (2r, 4r)-Phenylproline Derivatives as Potent Hsp90 Inhibitors
SSRN Electronic Journal·2024Open Access
BGS-2456 Is a Novel Potent Covalent Inhibitor of FLT3 That Highly Discriminates Against KIT and Is Not Toxic Toward Normal Hematopoiesis <i>in Vitro</i>
Blood·2023· 1 citedOpen Access
Alkyne as a Latent Warhead to Covalently Target SARS-CoV-2 Main Protease
Journal of Medicinal Chemistry·2023· 23 citedOpen Access
Development of Highly Fluorogenic Styrene Probes for Visualizing RNA in Live Cells
ACS Chemical Biology·2023· 14 citedOpen Access
Identification of Covalent Ligands – from Single Targets to Whole Proteome
Israel Journal of Chemistry·2023Open Access
SARS-CoV-2 couples evasion of inflammatory response to activated nucleotide synthesis
Proceedings of the National Academy of Sciences·2022· 40 citedOpen Access
Cortical Activation Reorganization of Cerebral Regions in Charcot– Marie–Tooth Patients: A Task-state Functional Magnetic Resonance Imaging Study
Journal of Orthopaedics and Sports Medicine·2022· 2 citedOpen Access
Reactivity-based chemical-genetic study of protein kinases
RSC Medicinal Chemistry·2022· 2 citedOpen Access
Abstract P156: Identification of previously unknown targets for approved small-molecule drugs using chemoproteomic platform IMTACTM
Molecular Cancer Therapeutics·2021
Targeting CTP Synthetase 1 to Restore Interferon Induction and Impede Nucleotide Synthesis in SARS-CoV-2 Infection
2021· 20 citedOpen Access
Basic analysis in TMT-based quantitative proteomic analysis
Figshare·2021Open Access
A two-pronged attack
Nature Chemical Biology·2020· 3 cited
Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma
Journal of Medicinal Chemistry·2020· 33 citedOpen Access
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Frequent Co-authors

Kevan M. Shokat(16), Gideon Bollag(9), Kevan M. Shokat(8), Prabha N. Ibrahim(5), Peter Hirth(4), Kam Y. J. Zhang(4), Dean R. Artis(4), Sung‐Hou Kim(4), Charles DeLisi(4), James Tsai(3), Jiazhong Zhang(3), Gaston Habets(3), Brian L. West(3), Adhirai Marimuthu(3), Hoa Nguyen(3), Joseph Schlessinger(3), K. B. Nolop(3), Daniel W. Fong(3), Robert P. Fisher(3), Hanna Cho(2)