Jennifer C. Darnell

University of Edinburgh — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index3.5kcitations12works0.02yr avg
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Research Topics

Genetics and Neurodevelopmental Disorders(12), RNA modifications and cancer(9), RNA Research and Splicing(5), Ubiquitin and proteasome pathways(3), Autism Spectrum Disorder Research(2)

Publications12 total

Excess ribosomal protein production unbalances translation in a model of Fragile X Syndrome
Nature Communications·2022· 51 citedOpen Access
Excess ribosomal protein production unbalances translation in Fragile X Syndrome
2022Open Access
FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory
eLife·2019· 119 citedOpen Access
Author response: FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory
2019· 2 citedOpen Access
FMRP binding to a ranked subset of long genes is revealed by coupled CLIP and TRAP in specific neuronal cell types
2019· 19 citedOpen Access
FMRP association with and regulation of Fragile X granules exhibit circuit-dependent requirements for the KH2 RNA binding domain
2018· 3 cited
Cholesterol levels in Fragile X syndrome
American Journal of Medical Genetics Part A·2014· 61 citedOpen Access
The translation of translational control by FMRP: therapeutic targets for FXS
Nature Neuroscience·2013· 488 citedOpen Access
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
Cell·2011· 2.1k citedOpen Access
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes
Genes & Development·2005· 289 citedOpen Access
Fragile X Mental Retardation Protein Is Associated with Translating Polyribosomes in Neuronal Cells
Journal of Neuroscience·2004· 271 citedOpen Access
The fragile X mental retardation protein, FMRP, recognizes G‐quartets
Mental Retardation and Developmental Disabilities Research Reviews·2004· 57 cited

Frequent Co-authors

Robert B. Darnell(7), Sarah J. Van Driesche(4), John J. Fak(4), Kirsty Sawicka(4), Claire Fraser(3), Christopher Y. Park(3), Chaolin Zhang(2), Ka Ying Sharon Hung(2), Giovanni Stefani(2), Caryn Hale(2), Jodi Gresack(2), Jin Joo Kang(2), Sang Soo Seo(2), Susana R. Louros(2), Natasha Anstey(2), Miguel A. Gonzalez‐Lozano(2), Callista B. Harper(2), Nicholas Verity(2), Owen Dando(2), Sophie R. Thomson(2)