Sam Gandy

James J. Peters VA Medical Center — United States

Medicine · Health Sciences

90h-index30.9kcitations499works2.62yr avg
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Research Topics

Alzheimer's disease research and treatments(265), Cholinesterase and Neurodegenerative Diseases(69), Traumatic Brain Injury Research(52), Dementia and Cognitive Impairment Research(44), Computational Drug Discovery Methods(43)

Publications495 total

miR155 triplicated in Down syndrome regulates hippocampal GABAergic neurogenesis in Alzheimer’s disease
2025Open Access
Endogenously generated Dutch-type Aβ nonfibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation
2025Open Access
Cognitive Aging and Neurodegenerative Disorders
Lifestyle Medicine·2025Open Access
Opportunities to encourage adoption of a biomarker‐enabled care pathway for Alzheimer's in primary care
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring·2025· 4 citedOpen Access
Alzheimer's disease‐associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain
Alzheimer s & Dementia·2024· 12 citedOpen Access
Implementing a biomarker‐enabled care pathway to accelerate identification of early‐stage Alzheimer’s disease in primary care
Alzheimer s & Dementia·2024Open Access
Nonfibrillar Dutch mutant amyloid beta (Aß) aggregates (oligomers) are associated with aging‐related synaptic dysfunction
Alzheimer s & Dementia·2024Open Access
Exposure duration and cerebral amyloidosis in the olfactory cortex of World Trade Center responders: A positron emission tomography and magnetic resonance imaging study
Journal of Alzheimer s Disease·2024· 1 citedOpen Access
Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice
Journal of Alzheimer s Disease·2024· 4 citedOpen Access
Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice
Frontiers in Aging Neuroscience·2024· 7 citedOpen Access
Real-world implications of the prospects for prevention of clinical Alzheimer's dementia
Genomic psychiatry :·2024· 1 citedOpen Access
Inpp5d deficiency exacerbates tau pathology and cognitive deficits in MAPT<sup>P301S</sup> mouse
Alzheimer s & Dementia·2023Open Access
Correction: miR155, TREM2, INPP5D: Disease stage and cell-type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy
Journal of Neuroinflammation·2023Open Access
Open peer commentary on “Prescribing anti‐amyloid immunotherapies to treat Alzheimer's disease: Fully informing patient decisions”
Alzheimer s & Dementia Translational Research & Clinical Interventions·2023· 1 citedOpen Access
News &amp; views: anti-amyloid antibodies and novel emerging approaches to Alzheimer’s disease in 2023
Molecular Neurodegeneration·2023· 11 citedOpen Access
miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy
Journal of Neuroinflammation·2023· 9 citedOpen Access
Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model
Frontiers in Dementia·2023· 1 citedOpen Access
Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice
2023· 1 citedOpen Access
Post-traumatic stress disorder may affect the progression of cognitive impairment in World Trade Center responders
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2023
Genetic architecture of plasma Alzheimer disease biomarkers
Human Molecular Genetics·2023· 14 citedOpen Access
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Frequent Co-authors

Paul Greengard(12), Michelle E. Ehrlich(10), Sangram S. Sisodia(9), Vahram Haroutunian(8), Eric E. Schadt(8), Joseph D. Buxbaum(7), Bin Zhang(7), Mary Seeger(6), Minghui Wang(6), Hilda H. Slunt(5), Allan I. Levey(5), Donald L. Price(5), Gopal Thinakaran(5), Pavel Katsel(5), Scott Noggle(5), David Borchelt(4), Michael K. Lee(4), Christer Nordstedt(4), Noam D. Beckmann(4), Gopal Thinakaran(3)