Randy Shen

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index1.4kcitations12works0.02yr avg
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Research Topics

Protein Tyrosine Phosphatases(8), Cytokine Signaling Pathways and Interactions(6), Protein Kinase Regulation and GTPase Signaling(3), Galectins and Cancer Biology(3), Immune Cell Function and Interaction(2)

Publications12 total

The protein tyrosine phosphatase Shp-2 regulates RhoA activity
UNC Libraries·2021Open Access
The Homeostasis But Not the Differentiation of T Cells Is Regulated by p27Kip1
The Journal of Immunology·2002· 20 citedOpen Access
Grap Negatively Regulates T-Cell Receptor-Elicited Lymphocyte Proliferation and Interleukin-2 Induction
Molecular and Cellular Biology·2002· 50 citedOpen Access
The protein tyrosine phosphatase Shp-2 regulates RhoA activity
Current Biology·2000· 134 citedOpen Access
Gab2, a New Pleckstrin Homology Domain-containing Adapter Protein, Acts to Uncouple Signaling from ERK Kinase to Elk-1
Journal of Biological Chemistry·1999· 134 citedOpen Access
A Deletion Mutation in the SH2-N Domain of Shp-2 Severely Suppresses Hematopoietic Cell Development
Molecular and Cellular Biology·1997· 165 citedOpen Access
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2
The EMBO Journal·1997· 474 citedOpen Access
Molecular Characterization of Specific Interactions between SHP-2 Phosphatase and JAK Tyrosine Kinases
Journal of Biological Chemistry·1997· 140 citedOpen Access
Involvement of SH2-containing Phosphotyrosine Phosphatase Syp in Erythropoietin Receptor Signal Transduction Pathways
Journal of Biological Chemistry·1995· 145 citedOpen Access
[34] Biochemical analysis of SH2 domain-mediated protein interactions
Methods in enzymology on CD-ROM/Methods in enzymology·1995· 14 cited
Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp.
PubMed·1994· 75 cited
Phylogenetic study of ribosomal DNA of cactophilic <i>Pichia</i> species by restriction mapping
Yeast·1993· 20 cited

Frequent Co-authors

Gen‐Sheng Feng(9), Tony Pawson(3), Cheng‐Kui Qu(2), Simone M. Schoenwaelder(2), Leslie Petch(2), David L. Williamson(2), Keith Burridge(2), Mark H. Kaplan(2), Tracy M. Saxton(1), Mark Henkemeyer(1), Stéphan Gasca(1), Derrick J. Rossi(1), Fouad Shalaby(1), Zhong-Qing Shi(1), Fong-Ying Tsai(1), Stuart H. Orkin(1), Tetsuzo Tauchi(1), Maureen E. Hoatlin(1), Grover C. Bagby(1), David Kabat(1)