Brian J. Platt

Drexel University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index1.4kcitations27works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(10), Neurotransmitter Receptor Influence on Behavior(5), Neuroendocrine regulation and behavior(5), Neuroscience and Neuropharmacology Research(3), Stress Responses and Cortisol(3)

Publications27 total

CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility
eLife·2020· 43 citedOpen Access
Author response: CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility
2019Open Access
CCDC 1950121: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
Modeling an Inflammation‐Related Depressive Phenotype in Mice Using Bacille Calmette‐Guérin
Current Protocols in Neuroscience·2013· 1 cited
A depressive phenotype induced by Bacille Calmette Guérin in ‘susceptible’ animals: sensitivity to antidepressants
Psychopharmacology·2012· 13 cited
2-(Pyrrolidin-1-yl)ethyl-3,4-dihydroisoquinolin-1(<i>2H</i>)-one Derivatives as Potent and Selective Histamine-3 Receptor Antagonists
Journal of Medicinal Chemistry·2012· 18 citedOpen Access
Pyrrolidin-3-yl-N-methylbenzamides as potent histamine 3 receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2011Open Access
The Metabotropic Glutamate Receptor 7 Allosteric Modulator AMN082: A Monoaminergic Agent in Disguise?
Journal of Pharmacology and Experimental Therapeutics·2011· 103 cited
The Synthesis and Biological Evaluation of Quinolyl-piperazinyl Piperidines as Potent Serotonin 5-HT<sub>1A</sub>Antagonists
Journal of Medicinal Chemistry·2010· 15 citedOpen Access
Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes
Proceedings of the National Academy of Sciences·2010· 82 citedOpen Access
Depression-like phenotype following chronic CB1 receptor antagonism
Neurobiology of Disease·2010· 155 citedOpen Access
Angiotensin IV elevates oxytocin levels in the rat amygdala and produces anxiolytic-like activity through subsequent oxytocin receptor activation
Psychopharmacology·2010· 28 cited
Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective α2A-adrenoceptor antagonism
The International Journal of Neuropsychopharmacology·2010· 26 citedOpen Access
Benzimidazole- and indole-substituted 1,3′-bipyrrolidine benzamides as histamine H3 receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2009· 16 citedOpen Access
Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist
Neuropharmacology·2009· 145 cited
Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT6 agonists
Bioorganic & Medicinal Chemistry·2009· 21 citedOpen Access
Preclinical characterization of WAY‐211612: a dual 5‐HT uptake inhibitor and 5‐HT<sub>1A</sub>receptor antagonist and potential novel antidepressant
British Journal of Pharmacology·2009· 9 citedOpen Access
CCDC 721524: Experimental Crystal Structure Determination
The Cambridge Structural Database·2009Open Access
Structure−Activity Relationships of the Cycloalkanol Ethylamine Scaffold: Discovery of Selective Norepinephrine Reuptake Inhibitors
Journal of Medicinal Chemistry·2008· 23 citedOpen Access
Schedule‐Induced Polydipsia: A Rat Model of Obsessive‐Compulsive Disorder
Current Protocols in Neuroscience·2008· 47 cited
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Frequent Co-authors

Sharon Rosenzweig‐Lipson(17), Lee E. Schechter(12), Chad E. Beyer(11), Jason M. Dwyer(8), Stacey J. Sukoff Rizzo(8), Albert J. Robichaud(7), Robert H. Ring(7), Qian Lin(6), Thomas A. Comery(6), Deborah L. Smith(4), Guoming Zhang(4), Sarah K. Leonard(4), Claudine Pulicicchio(4), Zoë A. Hughes(4), Sarah J. Neal Webb(4), Jessica E. Malberg(4), Nicholas J. Brandon(4), Jonathan Groß(4), Adedayo Adedoyin(4), Derek C. Cole(3)