Kenneth F. Bastow

University of North Carolina at Chapel Hill — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

52h-index8.6kcitations259works0.02yr avg
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Research Topics

Cancer therapeutics and mechanisms(54), Synthesis and biological activity(50), Natural product bioactivities and synthesis(31), Synthesis of Organic Compounds(29), Bioactive Compounds and Antitumor Agents(27)

Publications259 total

Identification of Novel 4′-O-Demethyl-epipodophyllotoxin Derivatives as Antitumor Agents Targeting Topoisomerase II
Molecules·2022· 5 citedOpen Access
Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition
UNC Libraries·2021Open Access
Elecanacin, a Novel New Naphthoquinone from the Bulb of Eleutherine americana
UNC Libraries·2021· 6 citedOpen Access
Antitumor agents 269. Non-aromatic ring-A neotanshinlactone analog, TNO, as a new class of potent antitumor agents
UNC Libraries·2021Open Access
Cytotoxic geranylflavonoids from Bonannia graeca
UNC Libraries·2020Open Access
Antitumor Agents. 274. A New Synthetic Strategy for E-Ring SAR Study of Antofine and Cryptopleurine Analogues
Figshare·2020Open Access
Antitumor Agents. 282. 2′-( R )- O -Acetylglaucarubinone, a Quassinoid from Odyendyea gabonensis As a Potential Anti-Breast and Anti-Ovarian Cancer Agent
UNC Libraries·2020· 1 citedOpen Access
Songaricalarins A–E, Cytotoxic Oplopane Sesquiterpenes from Ligularia songarica
Figshare·2020· 1 citedOpen Access
Cytotoxic Polyisoprenyl Benzophenonoids from Garcinia subelliptica
UNC Libraries·2020· 3 citedOpen Access
Bioactive Constituents from the Roots of Panax japonicus var. major and Development of a LC-MS/MS Method for Distinguishing between Natural and Artifactual Compounds
Figshare·2020· 3 citedOpen Access
Antitumor Agents 259. Design, Syntheses, and Structure−Activity Relationship Study of Desmosdumotin C Analogs
Figshare·2020Open Access
Antitumor Agents. 293. Nontoxic Dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylenedioxybiphenyl-2,2′-dicarboxylate (DDB) Analogues Chemosensitize Multidrug-Resistant Cancer Cells to Clinical Anticancer Drugs
Figshare·2020Open Access
Antitumor Agents. 284. New Desmosdumotin B Analogues with Bicyclic B-Ring as Cytotoxic and Antitubulin Agents
Figshare·2020Open Access
Antitumor Agents 268. Design, Synthesis, and Mechanistic Studies of New 9-Substituted Phenanthrene-Based Tylophorine Analogues as Potent Cytotoxic Agents
UNC Libraries·2020Open Access
Antitumor Agents. 280. Multidrug Resistance-Selective Desmosdumotin B Analogues
UNC Libraries·2020Open Access
Antitumor Agents. 250. † Design and Synthesis of New Curcumin Analogues as Potential Anti-Prostate Cancer Agents
Figshare·2020Open Access
Antitumor Agents. 289. Design, Synthesis, and Anti-Breast Cancer Activity in Vivo of 4-Amino-2 H -benzo[ h ]chromen-2-one and 4-Amino-7,8,9,10-tetrahydro-2 H -benzo[ h ]chromen-2-one Analogues with Improved Water Solubility
UNC Libraries·2020Open Access
Antitumor Agents. 266. Design, Synthesis, and Biological Evaluation of Novel 2-(Furan-2-yl)naphthalen-1-ol Derivatives as Potent and Selective Antibreast Cancer Agents
Figshare·2020Open Access
Camphoratins A−J, Potent Cytotoxic and Anti-inflammatory Triterpenoids from the Fruiting Body of Taiwanofungus camphoratus
UNC Libraries·2020Open Access
Altaicalarins A−D, Cytotoxic Bisabolane Sesquiterpenes from Ligularia altaica
Figshare·2020Open Access
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Frequent Co-authors

Kuo‐Hsiung Lee(41), Yuka Nakanishi(10), Yoko Tachibana(8), Tian-Shung Wu(7), Susan L. Morris‐Natschke(7), Kyoko Nakagawa‐Goto(6), Sheng-Chu Kuo(5), Chung-Ren Su(5), Hideji Itokawa(5), Yi-Nan Liu(5), Ernest Hamel(4), Qian Shi(4), Amooru G. Damu(4), Arnold Brossi(4), Fang‐Rong Chang(4), Yang‐Chang Wu(4), Zheng-Yu Yang(3), Peng Xia(3), Ying‐Chih Cheng(3), Ping‐Chung Kuo(3)