Arnold Brossi

University of North Carolina at Chapel Hill — United States

Chemistry · Physical Sciences

44h-index8.1kcitations326works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Chemical synthesis and alkaloids(58), Synthesis and biological activity(46), Cholinesterase and Neurodegenerative Diseases(38), Synthesis and Reactions of Organic Compounds(30), Alkaloids: synthesis and pharmacology(29)

Publications326 total

Design, synthesis and biological assessment of novel N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines and 3-substituted 2,6-dioxopiperidines for TNF-α inhibitory activity
UNC Libraries·2020Open Access
Inhibition of Human Acetyl- and Butyrylcholinesterase by Novel Carbamates of (−)- and (+)-Tetrahydrofurobenzofuran and Methanobenzodioxepine
Figshare·2020· 4 citedOpen Access
Antitumor Agents 252. Application of validated QSAR models to database mining: discovery of novel tylophorine derivatives as potential anticancer agents
UNC Libraries·2020· 2 citedOpen Access
A cellular model of inflammation for identifying TNF-α synthesis inhibitors
UNC Libraries·2020Open Access
Antitumor Agents. 272. Structure−Activity Relationships and In Vivo Selective Anti-Breast Cancer Activity of Novel Neo-tanshinlactone Analogues
Figshare·2020· 3 citedOpen Access
Antitumor agents 273. Design and synthesis of N-alkyl-thiocolchicinoids as potential antitumor agents
UNC Libraries·2020Open Access
Antitumor agents 270. Novel substituted 6-phenyl-4H-furo[3,2-c]pyran-4-one derivatives as potent and highly selective anti-breast cancer agents
UNC Libraries·2020Open Access
Long-acting anticholinesterases for myasthenia gravis: synthesis and activities of quaternary phenylcarbamates of neostigmine, pyridostigmine and physostigmine
UNC Libraries·2020Open Access
Preparation and Characterization of Tetrabenazine Enantiomers against Vesicular Monoamine Transporter 2
Figshare·2020Open Access
Design, synthesis and biological assessment of novel N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines and 3-substituted 2,6-dioxopiperidines for TNF-α inhibitory activity
Bioorganic & Medicinal Chemistry·2011· 23 citedOpen Access
Antitumor agents 273. Design and synthesis of N-alkyl-thiocolchicinoids as potential antitumor agents
Bioorganic & Medicinal Chemistry Letters·2010· 21 citedOpen Access
Long-acting anticholinesterases for myasthenia gravis: synthesis and activities of quaternary phenylcarbamates of neostigmine, pyridostigmine and physostigmine
Bioorganic & Medicinal Chemistry·2010· 41 citedOpen Access
Preparation and Characterization of Tetrabenazine Enantiomers against Vesicular Monoamine Transporter 2
ACS Medicinal Chemistry Letters·2010· 31 cited
Antitumor Agents. 272. Structure−Activity Relationships and In Vivo Selective Anti-Breast Cancer Activity of Novel Neo-tanshinlactone Analogues
Journal of Medicinal Chemistry·2010· 70 citedOpen Access
Antitumor agents 270. Novel substituted 6-phenyl-4H-furo[3,2-c]pyran-4-one derivatives as potent and highly selective anti-breast cancer agents
Bioorganic & Medicinal Chemistry·2009· 37 cited
A cellular model of inflammation for identifying TNF-α synthesis inhibitors
Journal of Neuroscience Methods·2009· 49 citedOpen Access
ChemInform Abstract: Syntheses of Aromatic Substituted 6′‐Thiothalidomides.
ChemInform·2009· 3 cited
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism
Proceedings of the National Academy of Sciences·2009· 573 citedOpen Access
Syntheses of Aromatic Substituted6′-Thiothalidomides
Synthesis·2008· 8 cited
ChemInform Abstract: Syntheses and Anticholinesterase Activities of Novel 3‐Aminocarbonylmethylene‐3‐methyl‐2,3‐dihydrobenzofuran‐5‐yl Carbamates.
ChemInform·2008
page 1 of 17Next →

Frequent Co-authors

Nigel H. Greig(16), Harold W. Holloway(12), Kuo‐Hsiung Lee(11), Debomoy K. Lahiri(9), Qian‐sheng Yu(9), Ernest Hamel(8), Kumar Sambamurti(5), Xue‐Feng Pei(5), Kenneth F. Bastow(5), Herman J. C. Yeh(4), Kenner C. Rice(4), Qian Shi(4), Weiming Luo(4), Tadanobu Utsuki(3), Donald K. Ingram(3), Qian-sheng Yu(3), Tony Giordano(3), David Tweedie(3), Olivier Boyé(3), Arthur E. Jacobson(3)