Larry L. Klein

University of Illinois Chicago — United States

Medicine · Health Sciences

26h-index1.7kcitations76works0.72yr avg
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Research Topics

HIV/AIDS drug development and treatment(17), HIV Research and Treatment(10), Hepatitis C virus research(8), Synthetic Organic Chemistry Methods(7), Cancer Treatment and Pharmacology(7)

Publications76 total

Unique Interactions of Novel Rufomycin “Click Chemistry” Analogs with <i>Mtb</i> ClpC1 and Implications
Journal of Medicinal Chemistry·2025
Enhancing rufomycin production by CRISPR/Cas9-based genome editing and promoter engineering in Streptomyces sp. MJM3502
Synthetic and Systems Biotechnology·2025· 2 citedOpen Access
Enhancing Rufomycin Production by CRISPR/Cas9-Based Genome Editing and Promoter Engineering in Streptomyces sp. MJM3502
SSRN Electronic Journal·2024Open Access
Unprecedented Benzoquinone Motifs Reveal Post-Oligomerizational Modification of Proanthocyanidins
The Journal of Organic Chemistry·2023· 4 citedOpen Access
Anti-Microbial Activity of Aliphatic Alcohols from Chinese Black Cardamom (Amomum tsao-ko) against Mycobacterium tuberculosis H37Rv
Plants·2022· 2 citedOpen Access
Design of Novel Phosphopantetheine Adenylyltransferase Inhibitors: A Potential New Approach to Tackle Mycobacterium tuberculosis
Current Topics in Medicinal Chemistry·2021· 7 citedOpen Access
CCDC 1957302: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
Antimycobacterial Rufomycin Analogues from <i>Streptomyces atratus</i> Strain MJM3502
Journal of Natural Products·2020· 49 citedOpen Access
Residual Complexity Does Impact Organic Chemistry and Drug Discovery: The Case of Rufomyazine and Rufomycin
The Journal of Organic Chemistry·2018· 40 citedOpen Access
QSAR-driven design, synthesis and discovery of potent chalcone derivatives with antitubercular activity
European Journal of Medicinal Chemistry·2017· 127 citedOpen Access
Development of Diazaquinomycin Class Antibiotics for the Treatment of Drug-Resistant TB Infections
2016
CCDC 707824: Experimental Crystal Structure Determination
The Cambridge Structural Database·2016Open Access
The Generally Useful Estimate of Solvent Systems (GUESS) method enables the rapid purification of methylpyridoxine regioisomers by countercurrent chromatography
Journal of Chromatography A·2015· 27 citedOpen Access
ChemInform Abstract: A Novel Indigoid Antituberculosis Agent
ChemInform·2014· 1 cited
Quantification of a Botanical Negative Marker without an Identical Standard: Ginkgotoxin in <i>Ginkgo biloba</i>
Journal of Natural Products·2014· 37 cited
A novel indigoid anti-tuberculosis agent
Bioorganic & Medicinal Chemistry Letters·2013· 10 citedOpen Access
Chlorinated Coumarins from the Polypore Mushroom <i>Fomitopsis officinalis</i> and Their Activity against <i>Mycobacterium tuberculosis</i>
Journal of Natural Products·2013· 54 citedOpen Access
ChemInform Abstract: Synthesis of Substituted Isatins.
ChemInform·2013
Synthesis of Trifunctional Bis-azide Photoaffinity Probe
Synthetic Communications·2013· 8 cited
CCDC 919159: Experimental Crystal Structure Determination
The Cambridge Structural Database·2013Open Access
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Frequent Co-authors

Dale J. Kempf(17), Clinton M. Yeung(15), John T. Randolph(11), David J. Grampovnik(10), Kennan C. Marsh(10), David A. DeGoey(9), Akhteruzzaman Molla(8), Paul A. Lartey(8), Warren M. Kati(7), Peggy Huang(6), William J. Flosi(6), Guido F. Pauli(6), Leping Li(6), Tatyana Dekhtyar(6), Vincent S. Stoll(6), Scott G. Franzblau(5), Rodger F. Henry(5), Jacob J. Plattner(5), Jacob J. Plattner(5), David C. Lankin(5)