Jacob J. Plattner

Abbott (United Kingdom) — United Kingdom

Chemistry · Physical Sciences

11h-index430citations11works0.02yr avg
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Research Topics

Synthetic Organic Chemistry Methods(3), Asymmetric Synthesis and Catalysis(2), Carbohydrate Chemistry and Synthesis(2), Chemical Synthesis and Analysis(2), Receptor Mechanisms and Signaling(2)

Publications11 total

Synthesis of 4''-Deoxy Motilides: Identification of a Potent and Orally Active Prokinetic Drug Candidate
Journal of Medicinal Chemistry·1995· 59 cited
Antitumor Activity of 9(R)-Dihydrotaxane Analogs
Journal of Medicinal Chemistry·1995· 32 cited
Synthesis and Biological Evaluation of C-3'-Modified Analogs of 9(R)-Dihydrotaxol
Journal of Medicinal Chemistry·1994· 29 cited
Synthesis and Antifungal Activity of 1,3,2-Benzodithiazole S-Oxides
Journal of Medicinal Chemistry·1994· 12 cited
Synthesis and antibacterial activities of C-21 functionalized derivatives of (9R)-9-amino-9-deoxoerythromycins A and B
Journal of Medicinal Chemistry·1991· 11 cited
Synthesis and antitumor activity of structural analogs of the epipodophyllotoxins
Journal of Medicinal Chemistry·1991· 23 cited
Synthesis, antibacterial activities, and pharmacological properties of enantiomers of temafloxacin hydrochloride
Journal of Medicinal Chemistry·1991· 51 cited
Cyclobut-A and cyclobut-G: broad-spectrum antiviral agents with potential utility for the therapy of AIDS
Journal of Medicinal Chemistry·1990· 121 cited
LH-RH antagonists: design and synthesis of a novel series of peptidomimetics
Journal of Medicinal Chemistry·1989· 44 citedOpen Access
Renin inhibitors Improvements in the stability and biological activity of small peptides containing novel Leu‐Val replacements
FEBS Letters·1988· 23 cited
New inhibitors of human renin that contain novel Leu-Val replacements. Examination of the P1 site
Journal of Medicinal Chemistry·1988· 25 citedOpen Access

Frequent Co-authors

Larry L. Klein(5), Paul A. Lartey(4), Clinton M. Yeung(4), Jacob J. Clement(3), Thomas J. Perun(3), Ramin Faghih(2), Dwight J. Hardy(2), Clarence J. Maring(2), David J. Grampovnik(2), Jay R. Luly(2), Daniel W. Norbeck(1), Earl R. Kern(1), Seiji Hayashi(1), William Rosenbrook(1), Hing L. Sham(1), Thomas Herrin(1), John E. Erickson(1), Hugh N. Nellans(1), Albert Petersen(1), Carla M. Edwards(1)