John McNeish

GlaxoSmithKline (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index2.9kcitations26works0.02yr avg
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Research Topics

Pluripotent Stem Cells Research(6), CRISPR and Genetic Engineering(4), 3D Printing in Biomedical Research(4), Cholesterol and Lipid Metabolism(4), Animal Genetics and Reproduction(4)

Publications26 total

Measurement of optical action potentials and calcium transients in hIPSC-derived cardiomyocytes using the novel Optopatch© fluorescent protein platform
Journal of Pharmacological and Toxicological Methods·2015
From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical Trial
Cell stem cell·2015· 81 citedOpen Access
Amitriptyline induces glial-cell line derived neurotrophic factor in retinal cells in vivo and in vitro
2014· 1 cited
In Vivo Mitogen-Activated Protein Kinase Activation Scaffold Which Facilitates Kinase Suppressor of Ras (KSR) Is a
2014
Book Review: Bringing Stem Cell Science to the Classrooms
Regenerative Medicine·2011Open Access
Pharma's Developing Interest in Stem Cells
Cell stem cell·2010· 83 citedOpen Access
High-throughput Screening in Embryonic Stem Cell-derived Neurons Identifies Potentiators of α-Amino-3-hydroxyl-5-methyl-4-isoxazolepropionate-type Glutamate Receptors
Journal of Biological Chemistry·2010· 67 citedOpen Access
KSR2 Is an Essential Regulator of AMP Kinase, Energy Expenditure, and Insulin Sensitivity
Cell Metabolism·2009· 149 citedOpen Access
Stem cells as screening tools in drug discovery
Current Opinion in Pharmacology·2007· 35 cited
Circadian Rhythm Phenotype of 5-HT₇ Receptor Knockout Mice: 5-HT and 8-OH-DPAT-Induced Phase Advances of SCN Neuronal Firing
Journal of Biological Rhythms·2005· 50 citedOpen Access
Embryonic stem cells in drug discovery
Nature Reviews Drug Discovery·2004· 168 cited
PDE10A knockout mice: Behavioral characterization and effects of papaverine, a PDE10A inhibitor
Schizophrenia Research·2003· 2 cited
Kinase Suppressor of Ras (KSR) Is a Scaffold Which Facilitates Mitogen-Activated Protein Kinase Activation In Vivo
Molecular and Cellular Biology·2002· 273 citedOpen Access
The Correlation of ATP-binding Cassette 1 mRNA Levels with Cholesterol Efflux from Various Cell Lines
Journal of Biological Chemistry·2000· 298 citedOpen Access
ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine.
Nature Cell Biology·2000· 523 cited
High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1
Proceedings of the National Academy of Sciences·2000· 539 citedOpen Access
Deficiency of the Stress Kinase P38α Results in Embryonic Lethality
The Journal of Experimental Medicine·2000· 268 citedOpen Access
Phenotypic characterization and analysis of allogeneic T cell responses in ZAP-70 dominant negative transgenic mice
Clinical & Experimental Immunology·1997· 5 citedOpen Access
Expression of human lecithin:cholesterol acyltransferase in transgenic mice: effects on cholesterol efflux, esterification, and transport
Journal of Lipid Research·1997· 56 citedOpen Access
Treatment With Growth Hormone and Dexamethasone in Mice Transgenic for Human Islet Amyloid Polypeptide Causes Islet Amyloidosis and β-Cell Dysfunction
Diabetes·1996· 89 cited
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Frequent Co-authors

Jeffrey L. Stock(6), S. Steven Potter(5), Andréy S. Shaw(4), Marsha L. Roach(3), Lori Royer(3), Omar L. Francone(3), Oleg V. Chaika(3), Deborah K. Morrison(3), Robert E. Lewis(3), Christopher A. Gabel(2), Kenneth L. Hoppe(2), Cyril Broccardo(2), Giovanna Chimini(2), Richard Burack(2), Robert L. Kortum(2), Maryam Afkarian(2), William J. Muller(2), Kenneth M. Murphy(2), Melanie Allen(2), John Hambor(2)