John A. Kemp

Neuroscience · Life Sciences

61h-index12.1kcitations154works1.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(92), Ion channel regulation and function(31), Receptor Mechanisms and Signaling(31), Alzheimer's disease research and treatments(15), Memory and Neural Mechanisms(15)

Publications152 total

Uremic toxins and inflammatory profile of patients with chronic kidney disease: A cross-sectional study involving non-dialysis, hemodialysis and peritoneal dialysis
Clinical Nutrition ESPEN·2023· 1 citedOpen Access
Magnesium and inflammation: A focus on chronic kidney diseases patients
Clinical Nutrition ESPEN·2023
Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease
Journal of Neuroinflammation·2023· 13 citedOpen Access
SDI-118, a novel procognitive SV2A modulator: First-in-human randomized controlled trial including PET/fMRI assessment of target engagement
Frontiers in Pharmacology·2023· 9 citedOpen Access
The impact of integrating mental health services within a prison setting
Mental Health Review Journal·2022· 3 cited
A Modest Increase in 11C-PK11195-Positron Emission Tomography TSPO Binding in Depression Is Not Associated With Serum C-Reactive Protein or Body Mass Index
Biological Psychiatry Cognitive Neuroscience and Neuroimaging·2021· 29 citedOpen Access
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice
Brain·2019· 225 citedOpen Access
Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo
Journal of Alzheimer s Disease·2018· 40 citedOpen Access
Emergence of early alterations in network oscillations and functional connectivity in a tau seeding mouse model of Alzheimer’s disease pathology
Scientific Reports·2017· 98 citedOpen Access
Profiling the dynamics of CSF and plasma Aβ reduction after treatment with JNJ‐54861911, a potent oral BACE inhibitor
Alzheimer s & Dementia Translational Research & Clinical Interventions·2016· 59 citedOpen Access
ID 389 – Studies of neuronal circuits underlying information processing through late P300 event-related potentials in rats
Clinical Neurophysiology·2016
ID 388 – Dynamic alterations of brain network oscillations in a Tau seeding mouse model of Alzheimer’s disease
Clinical Neurophysiology·2016
Age‑dependent concomitant changes in synaptic function and GABAergic pathway in the APP/PS1 mouse model
Acta Neurobiologiae Experimentalis·2016· 20 citedOpen Access
Translational neurophysiological markers for activity of the metabotropic glutamate receptor (mGluR2) modulator JNJ-40411813: Sleep EEG correlates in rodents and healthy men
Neuropharmacology·2015· 14 cited
P4‐270: Study of spontaneous seizure in a mouse model of Alzheimer's disease
Alzheimer s & Dementia·2015
Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice
Neurobiology of Disease·2014· 208 citedOpen Access
O3‐12‐05: INTRACEREBRAL INJECTION OF PREFORMED SYNTHETIC TAU FIBRILS INITIATES WIDESPREAD TAUOPATHY AND NEURONAL LOSS IN THE BRAINS OF TAU TRANSGENIC MICE
Alzheimer s & Dementia·2014· 2 cited
Comment on “ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models”
Science·2013· 126 cited
Bexarotene treatment does not clear β-Amyloid in an AD mouse model and Beagle dogs
Molecular Neurodegeneration·2013· 1 citedOpen Access
Abstract 2770: An open-label comparative study of the pharmacokinetics and tolerability of zibotentan (ZD4054) in subjects with mild, moderate, or severe hepatic impairment, or normal hepatic function
Cancer Research·2010
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Frequent Co-authors

James N.C. Kew(12), Vincent Mutel(10), Alan C. Foster(7), Paul D. Leeson(6), Adam M. Sillito(6), Guy A. Higgins(5), G.N. Woodruff(4), John Richards(4), Geo Adam(4), Tony Priestley(3), Gerhard Trube(3), Pari Malherbe(3), Frédéric Knoflach(3), J. G. Richards(3), Diederik Moechars(3), Abdel‐Mouttalib Ouagazzal(3), Horst Bluethmann(3), Robert W. Carling(3), Angela M. Moseley(3), Graeme I. Stevenson(3)