E. Joan Blanchette‐Mackie

National Institutes of Health — United States

Medicine · Health Sciences

44h-index8.4kcitations80works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Lysosomal Storage Disorders Research(21), Lipid metabolism and biosynthesis(17), Cellular transport and secretion(14), Lipid Membrane Structure and Behavior(13), Adipose Tissue and Metabolism(13)

Publications80 total

P-39: Dissection of the insulin responsive GLUT4 subcellular trafficking pathway in rat adipose cells using the PI3-kinase inhibitor wortmannin: A confocal microscopy approach
Experimental and Clinical Endocrinology & Diabetes·2009
Transduction of rat pancreatic islets with pseudotyped adeno-associated virus vectors
Virology Journal·2009· 13 citedOpen Access
Targeted Mutation of the MLN64 START Domain Causes Only Modest Alterations in Cellular Sterol Metabolism
Journal of Biological Chemistry·2004· 93 citedOpen Access
Differential trafficking of the Niemann‐Pick C1 and 2 proteins highlights distinct roles in late endocytic lipid trafficking
Acta Paediatrica·2003· 47 cited
A Sperm-Associated WD Repeat Protein Orthologous to <i>Chlamydomonas</i> PF20 Associates with Spag6, the Mammalian Orthologue of <i>Chlamydomonas</i> PF16
Molecular and Cellular Biology·2002· 77 citedOpen Access
A Human Novel Gene DERPC Located on 16q22.1 Inhibits Prostate Tumor Cell Growth and Its Expression Is Decreased in Prostate and Renal Tumors
Molecular Medicine·2002· 15 citedOpen Access
MLN64 Mediates Mobilization of Lysosomal Cholesterol to Steroidogenic Mitochondria
Journal of Biological Chemistry·2002· 166 citedOpen Access
Cessation of rapid late endosomal tubulovesicular trafficking in Niemann–Pick type C1 disease
Proceedings of the National Academy of Sciences·2001· 146 citedOpen Access
Sterol-modulated Glycolipid Sorting Occurs in Niemann-Pick C1 Late Endosomes
Journal of Biological Chemistry·2001· 111 citedOpen Access
Determinants of NPC1 Expression and Action: Key Promoter Regions, Posttranscriptional Control, and the Importance of a “Cysteine-Rich” Loop
Experimental Cell Research·2000· 50 cited
Intracellular cholesterol trafficking: role of the NPC1 protein
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2000· 112 cited
Adrenal and liver in normal and cld/cld mice synthesize and secrete hepatic lipase, but the lipase is inactive in cld/cld mice
Journal of Lipid Research·2000· 12 citedOpen Access
NPC1-Containing Compartment of Human Granulosa-Lutein Cells: A Role in the Intracellular Trafficking of Cholesterol Supporting Steroidogenesis
Experimental Cell Research·2000· 51 cited
Mutations in the Leucine Zipper Motif and Sterol-sensing Domain Inactivate the Niemann-Pick C1 Glycoprotein
Journal of Biological Chemistry·1999· 133 citedOpen Access
Induction of Endocytic Vesicles by Exogenous C6-ceramide
Journal of Biological Chemistry·1999· 59 citedOpen Access
The Niemann-Pick C1 Protein Resides in a Vesicular Compartment Linked to Retrograde Transport of Multiple Lysosomal Cargo
Journal of Biological Chemistry·1999· 374 citedOpen Access
Localization of Niemann–Pick C1 protein in astrocytes: Implications for neuronal degeneration in Niemann– Pick type C disease
Proceedings of the National Academy of Sciences·1999· 176 cited
Niemann-Pick C1 protein: Obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization
Proceedings of the National Academy of Sciences·1999· 163 cited
Combined lipase deficiency (cld/cld) in mice affects differently post-translational processing of lipoprotein lipase, hepatic lipase and pancreatic lipase
Chemistry and Physics of Lipids·1998· 23 cited
Sickling of nucleated erythroid precursors from patients with sickle cell anemia.
PubMed·1998· 12 cited
page 1 of 4Next →

Frequent Co-authors

Nancy K. Dwyer(18), Peter G. Pentchev(11), Edward B. Neufeld(9), Jerome F. Strauss(8), Robert O. Scow(8), Shutish C. Patel(7), Adele Cooney(6), R O Scow(6), Roscoe O. Brady(5), Hidemichi Watari(5), Constantine Londos(4), L M Amende(4), Hiroshi Masuno(4), Eugene D. Carstea(3), Marcella Comly(3), T Barber(3), Howard S. Kruth(3), Marcy Comly(3), John A. Hanover(3), P. G. Pentchev(3)