Gillian Greig

TransCanada (Canada) — Canada

Medicine · Health Sciences

29h-index4.8kcitations50works0.02yr avg
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Research Topics

Inflammatory mediators and NSAID effects(21), Receptor Mechanisms and Signaling(9), Asthma and respiratory diseases(7), Synthesis and biological activity(7), Chromosomal and Genetic Variations(6)

Publications50 total

Potent and highly selective DP1 antagonists with 2,3,4,9-tetrahydro-1H-carbazole as pharmacophore
Bioorganic & Medicinal Chemistry Letters·2010· 29 citedOpen Access
Discovery of potent and selective DP1 receptor antagonists in the azaindole series
Bioorganic & Medicinal Chemistry Letters·2009· 14 citedOpen Access
CCDC 721867: Experimental Crystal Structure Determination
The Cambridge Structural Database·2009Open Access
Identification of prostaglandin D2 receptor antagonists based on a tetrahydropyridoindole scaffold
Bioorganic & Medicinal Chemistry Letters·2008· 44 citedOpen Access
CCDC 601363: Experimental Crystal Structure Determination
The Cambridge Structural Database·2008Open Access
Discovery of a Potent and Selective Prostaglandin D<sub>2</sub> Receptor Antagonist, [(3<i>R</i>)-4-(4-Chloro- benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[<i>b</i>]indol-3-yl]-acetic Acid (MK-0524)
Journal of Medicinal Chemistry·2007· 170 citedOpen Access
Comparison between two classes of selective EP3 antagonists and their biological activities
Bioorganic & Medicinal Chemistry Letters·2006· 32 citedOpen Access
Identification of an indole series of prostaglandin D2 receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2006· 21 citedOpen Access
Human Hematopoietic PGD2 Synthase: Inhibition by 15-deoxy–12,14-PGJ2 and Sulindac Sulfide, and Localization to Mast Cells
Journal of Allergy and Clinical Immunology·2006
CCDC 297169: Experimental Crystal Structure Determination
The Cambridge Structural Database·2006Open Access
CCDC 297363: Experimental Crystal Structure Determination
The Cambridge Structural Database·2006Open Access
Preferential inhibition of human phosphodiesterase 4 by ibudilast
Life Sciences·2005· 60 cited
The C3a receptor antagonist SB 290157 has agonist activity
Immunology Letters·2005· 92 cited
Identification of a Potent and Selective Synthetic Agonist at the CRTH2 Receptor
Molecular Pharmacology·2005· 48 cited
2,3-Diarylthiophenes as selective EP1 receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2005· 37 citedOpen Access
Structure–activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP3 antagonists
Bioorganic & Medicinal Chemistry Letters·2004· 28 citedOpen Access
Benzimidazoles as New Potent and Selective DP Antagonists for the Treatment of Allergic Rhinitis.
ChemInform·2004
Benzimidazoles as new potent and selective DP antagonists for the treatment of allergic rhinitis
Bioorganic & Medicinal Chemistry Letters·2004· 78 citedOpen Access
Discovery of a Potent and Selective Agonist of the Prostaglandin EP<sub>4</sub> Receptor.
ChemInform·2003
Discovery of a potent and selective agonist of the prostaglandin EP4 receptor
Bioorganic & Medicinal Chemistry Letters·2003· 83 citedOpen Access
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Frequent Co-authors

Gary P. O’Neill(21), Stacia Kargman(17), Robert J. Gordon(14), Zhaoyin Wang(14), Kathleen M. Metters(13), Christine Brideau(13), Danielle Denis(13), Deborah Slipetz(12), Nicole Sawyer(11), Denis Riendeau(11), Sonia Lamontagne(11), Elizabeth Wong(10), Nicolas Lachance(10), Robert N. Young(9), Wanda Cromlish(9), Nathalie Chauret(9), Robert Zamboni(8), Nancy N. Tsou(8), Diane Ethier(7), Petpiboon Prasit(7)