Sherwin Wilk

Icahn School of Medicine at Mount Sinai — United States

Medicine · Health Sciences

45h-index6.7kcitations159works0.02yr avg
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Research Topics

Peptidase Inhibition and Analysis(59), Neuropeptides and Animal Physiology(50), Ubiquitin and proteasome pathways(24), Neurotransmitter Receptor Influence on Behavior(16), Neuroscience and Neuropharmacology Research(12)

Publications156 total

Xaa-Arg dipeptidase
Handbook of Proteolytic Enzymes·2025
Aspartyl aminopeptidase
Handbook of Proteolytic Enzymes·2025
Alanine carboxypeptidase
Handbook of Proteolytic Enzymes·2025
Intracellular Peptide Turnover: Properties and Physiological Significance of the Major Peptide Hydrolases of Brain Cytosol
2020
The Diagnosis of Pheochromocytoma
2015· 30 cited
Chloride channel ClC-5 binds to aspartyl aminopeptidase to regulate renal albumin endocytosis
American Journal of Physiology-Renal Physiology·2015· 11 cited
6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes α-synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation.
Journal of Biological Chemistry·2013Open Access
Xaa-Arg Dipeptidase
Handbook of Proteolytic Enzymes·2012
Alanine Carboxypeptidase
Handbook of Proteolytic Enzymes·2012
Aspartyl Aminopeptidase
Handbook of Proteolytic Enzymes·2012
Oligomers of Mutant Glial Fibrillary Acidic Protein (GFAP) Inhibit the Proteasome System in Alexander Disease Astrocytes, and the Small Heat Shock Protein αB-Crystallin Reverses the Inhibition
Journal of Biological Chemistry·2010· 98 citedOpen Access
Title Page / Table of Contents
Neurodegenerative Diseases·2007Open Access
Study on the Putative Contribution of Caspases and the Proteasome to the Degradation of Aph-1a and Pen-2
Neurodegenerative Diseases·2007· 4 cited
Crystal Structures of DPP-IV (CD26) from Rat Kidney Exhibit Flexible Accommodation of Peptidase-Selective Inhibitors
Biochemistry·2006· 41 citedOpen Access
Pyroglutamyl peptidase type I from <i>Trypanosoma brucei</i>: a new virulence factor from African trypanosomes that de-blocks regulatory peptides in the plasma of infected hosts
Biochemical Journal·2006· 59 citedOpen Access
Catabolism of endogenous and overexpressed APH1a and PEN2: evidence for artifactual involvement of the proteasome in the degradation of overexpressed proteins
Biochemical Journal·2006· 15 citedOpen Access
6-Hydroxydopamine but Not 1-Methyl-4-phenylpyridinium Abolishes α-Synuclein Anti-apoptotic Phenotype by Inhibiting Its Proteasomal Degradation and by Promoting Its Aggregation
Journal of Biological Chemistry·2006· 50 citedOpen Access
JLK Inhibitors : Isocoumarin Compounds as Putative Probes to Selectively Target the gama-Secretase Pathway
HAL (Le Centre pour la Communication Scientifique Directe)·2005
Proteases and Signaling
Science s STKE·2005· 2 cited
Apoptosis
Science s STKE·2005· 4 cited
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Frequent Co-authors

Marian Orłowski(13), Elizabeth Wilk(5), Stanley E. Gitlow(4), Samuel Gershon(3), Maria E. Figueiredo‐Pereira(3), Dennis P. Healy(3), Milton Mendlowitz(3), Gregory Sathananthan(2), Stevens Pearce(2), Baron Shopsin(2), Donald D. Clarke(2), Eric N. Chauvel(2), Catherine Llorens‐Cortés(2), Pascale Coric(2), Bernárd P. Roques(2), Marie‐Claude Fournié‐Zaluski(2), Ronald P. Magnusson(2), Eric Watson(2), Barbara Travis(2), Theodore C. Friedman(2)