Kuo-Fen Lee

Salk Institute for Biological Studies — United States

Neuroscience · Life Sciences

27h-index8.0kcitations30works0.02yr avg
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Research Topics

Nerve injury and regeneration(7), Ion channel regulation and function(5), Stress Responses and Cortisol(5), Neurogenesis and neuroplasticity mechanisms(4), HER2/EGFR in Cancer Research(4)

Publications30 total

Blocking skeletal muscle DHPRs/Ryr1 prevents neuromuscular synapse loss in mutant mice deficient in type III Neuregulin 1 (CRD-Nrg1)
PLoS Genetics·2019· 14 citedOpen Access
Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal
PLoS Genetics·2019· 21 citedOpen Access
p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling
Cell Reports·2017· 29 citedOpen Access
Magnetically-responsive silica–gold nanobowls for targeted delivery and SERS-based sensing
Nanoscale·2016· 32 cited
Brains, Genes, and Primates
Neuron·2015· 5 citedOpen Access
The Epidermal Growth Factor Receptor Critically Regulates Endometrial Function during Early Pregnancy
PLoS Genetics·2014· 106 citedOpen Access
Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease
Molecular Cell·2012· 152 citedOpen Access
Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms
Proceedings of the National Academy of Sciences·2010· 43 cited
erbB2 is required for G protein-coupled receptor signaling in the heart
Proceedings of the National Academy of Sciences·2006· 59 citedOpen Access
Neurotransmitter Acetylcholine Negatively Regulates Neuromuscular Synapse Formation by a Cdk5-Dependent Mechanism
Neuron·2005· 221 citedOpen Access
Cholinergic Input Is Required during Embryonic Development to Mediate Proper Assembly of Spinal Locomotor Circuits
Neuron·2005· 155 citedOpen Access
Defective Neuromuscular Synapses in Mice Lacking Amyloid Precursor Protein (APP) and APP-Like Protein 2
Journal of Neuroscience·2005· 281 citedOpen Access
Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells
Development·2004· 329 citedOpen Access
Somatic Mutation of <b> <i>p53</i> </b> Leads to Estrogen Receptor α-Positive and -Negative Mouse Mammary Tumors with High Frequency of Metastasis
Cancer Research·2004· 122 cited
Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function
Proceedings of the National Academy of Sciences·2003· 374 citedOpen Access
Aberrant Patterning of Neuromuscular Synapses in Choline Acetyltransferase-Deficient Mice
Journal of Neuroscience·2003· 169 citedOpen Access
Colonic Epithelial Expression of ErbB2 Is Required for Postnatal Maintenance of the Enteric Nervous System
Neuron·2003· 68 citedOpen Access
Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior
Nature Genetics·2002· 172 cited
ErbB2 is essential in the prevention of dilated cardiomyopathy
Nature Medicine·2002· 909 cited
Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse
Nature·2001· 524 cited
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Frequent Co-authors

Weichun Lin(8), Bertha Dominguez(7), Wylie Vale(6), George W. Smith(5), Angelo Contarino(4), George F. Koob(4), Rudolf Jaenisch(4), Fred H. Gage(4), Steven A. Crone(3), F. Dellu(3), Lisa Gold(3), Yoshie Sugiura(3), Yusu Gu(2), Kirk L. Peterson(2), Yelena Marchuk(2), Patrik Ernfors(2), Samuel L. Pfaff(2), Jiefei Yang(2), Prafulla Aryal(2), Eugene P. Brandon(2)