A. W. Ford‐Hutchinson

Merck Canada Inc. (Canada) — Canada

Medicine · Health Sciences

37h-index7.3kcitations131works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Asthma and respiratory diseases(54), Inflammatory mediators and NSAID effects(34), Allergic Rhinitis and Sensitization(18), Eicosanoids and Hypertension Pharmacology(14), Immune Response and Inflammation(13)

Publications130 total

Leukotrienes as mediators of skin inflammation
British Journal of Dermatology·2006· 41 cited
Enzymes involved in the production of leukotrienes and related molecules
1998· 5 cited
ChemInform Abstract: Discovery of L‐740,515, a Potent Thienopyridine cysLT1 Receptor (LTD4 Receptor) Antagonist.
ChemInform·1996
Discovery of L-740,515, a potent thienopyridine cysLT1 receptor (LTD4 receptor) antagonist
Bioorganic & Medicinal Chemistry Letters·1995· 7 cited
Evolution of a series of non-quinoline leukotriene D4 receptor antagonist; synthesis and sar of benzothiazoles and thiazoles substituted benzyl alcohols as potent LTD4 antagonists
Bioorganic & Medicinal Chemistry Letters·1995· 31 cited
ChemInform Abstract: Discovery of MK‐0476, a Potent and Orally Active Leukotriene D4 Receptor Antagonist Devoid of Peroxisomal Enzyme Induction.
ChemInform·1995· 10 cited
Antiasthmatic effects of a leukotriene biosynthesis inhibitor (MK-0591) in allergic dogs
Journal of Applied Physiology·1995· 11 cited
Discovery of MK-0476, a potent and orally active leukotriene D4 receptor antagonist devoid of peroxisomal enxyme induction
Bioorganic & Medicinal Chemistry Letters·1995· 100 cited
Leukotriene antagonists and inhibitors: clinical applications.
PubMed·1995· 4 cited
Regulation of leukotriene biosynthesis
Cancer and Metastasis Reviews·1994· 37 cited
Regulation of the production and action of leukotrienes: Implications in human disease
Pathophysiology·1994Open Access
Leukotriene C<sub>4</sub> Synthase and 5‐Lipoxygenase Activating Protein
Annals of the New York Academy of Sciences·1994· 9 cited
ChemInform Abstract: The Discovery of L‐699,392, a Novel Potent and Orally Active Leukotriene D4 Receptor Antagonist.
ChemInform·1994
5-LIPOXYGENASE
Annual Review of Biochemistry·1994· 363 cited
Effect of FLAP antagonist MK-0591 on leukotriene production and ozone-induced airway responses in dogs
Journal of Applied Physiology·1994· 14 cited
The discovery of L-699,392, a novel potent and orally active leukotriene D4 receptor antagonist
Bioorganic & Medicinal Chemistry Letters·1994· 12 cited
5-Lipoxygenase
Annual Review of Biochemistry·1994
Chronic leukotriene inhibition in the rat fails to modify the toxicological effects of a cyclooxygenase inhibitor
Canadian Journal of Physiology and Pharmacology·1993· 4 cited
Leukotriene antagonists and inhibitors as modulators of IgE-mediated reactions
Springer Seminars in Immunopathology·1993· 13 cited
Leukotriene generation and metabolism in dogs: inhibition of biosynthesis by MK-0591.
Journal of Pharmacology and Experimental Therapeutics·1993· 14 cited
page 1 of 7Next →

Frequent Co-authors

M. J. H. Smith(13), M.A. Bray(8), Robert Zamboni(8), C. S. McFarlane(8), Robert N. Young(7), Thomas R. Jones(7), P. Masson(7), R. Hamel(6), L. Charette(5), John R. Walker(5), S. Charleson(5), Éric Champion(4), Joshua Rokach(4), H. Piechuta(4), John W. Gillard(3), Michel Belley(3), Serge Léger(3), Robert N. DeHaven(3), Marc Labelle(3), J. Y. GAUTHIER(3)