Wim J.M. Van de Ven

KU Leuven — Belgium

Biochemistry, Genetics and Molecular Biology · Life Sciences

46h-index6.3kcitations179works0.02yr avg
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Research Topics

Cellular transport and secretion(21), Virus-based gene therapy research(19), Endoplasmic Reticulum Stress and Disease(14), RNA Research and Splicing(13), Genomics and Chromatin Dynamics(12)

Publications176 total

PLAG1 deficiency impairs spermatogenesis and sperm motility in mice
Scientific Reports·2017· 27 citedOpen Access
Synthesis and Characterization of Curcumin-Functionalized HP-<i>β</i>-CD-Modified GoldMag Nanoparticles as Drug Delivery Agents
Journal of Nanoscience and Nanotechnology·2016· 20 cited
Emerging role of PLAG1 as a regulator of growth and reproduction
Journal of Endocrinology·2015· 94 citedOpen Access
Curcumin affects proprotein convertase activity: Elucidation of the molecular and subcellular mechanism
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2013· 11 cited
Polyphenols Can Inhibit Furin In Vitro As A Result of the Reactivity of their Auto-oxidation Products to Proteins
Current Medicinal Chemistry·2013· 19 cited
A Novel Magnetic Nanoparticle Drug Carrier for Enhanced Cancer Chemotherapy
PLoS ONE·2012· 39 citedOpen Access
Generation and characterization of non-competitive furin-inhibiting nanobodies
Biochemical Journal·2012· 32 citedOpen Access
Limitations of Inhibitory Activities of Polyphenols on Furin-Mediated Substrate Processing
Current Medicinal Chemistry·2012· 17 cited
Abstract 4627: Generation and characterization of non-competitive furin-inhibiting nanobodies
Cancer Research·2012
<i>Pdx1</i>- and <i>Ngn3-Cre</i>-Mediated <i>PLAG1</i> Expression in the Pancreas Leads to Endocrine Hormone Imbalances That Affect Glucose Metabolism
Cell Transplantation·2011· 5 citedOpen Access
Increased β-Cell Mass by Islet Transplantation and <i>PLAG1</i> Overexpression Causes Hyperinsulinemic Normoglycemia and Hepatic Insulin Resistance in Mice
Diabetes·2010· 14 citedOpen Access
SCAMP5, NBEA and AMISYN: three candidate genes for autism involved in secretion of large dense-core vesicles
Human Molecular Genetics·2010· 94 citedOpen Access
Targeted disruption of the mouse Lipoma Preferred Partner gene
Biochemical and Biophysical Research Communications·2008· 27 cited
The human pseudoxanthoma elasticum gene ABCC6 is transcriptionally regulated by PLAG family transcription factors
Human Genetics·2008· 19 cited
Role of furin in granular acidification in the endocrine pancreas: Identification of the V-ATPase subunit Ac45 as a candidate substrate
Proceedings of the National Academy of Sciences·2008· 81 citedOpen Access
Adenomyoepitheliomatous lesions of the mammary glands in transgenic mice with targeted PLAG1 overexpression
International Journal of Cancer·2008· 18 citedOpen Access
Lpp is involved in Wnt/PCP signaling and acts together with Scrib to mediate convergence and extension movements during zebrafish gastrulation
Developmental Biology·2008· 29 cited
Position effect leading to haploinsufficiency in a mosaic ring chromosome 14 in a boy with autism
European Journal of Human Genetics·2008· 26 citedOpen Access
Loss of the PlagL2 Transcription Factor Affects Lacteal Uptake of Chylomicrons
Cell Metabolism·2007· 54 citedOpen Access
HMGA2 Regulates Transcription of the <i>Imp2</i> Gene via an Intronic Regulatory Element in Cooperation with Nuclear Factor-κB
Molecular Cancer Research·2007· 91 cited
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Frequent Co-authors

Anton Roebroek(15), John W.M. Creemers(10), Marianne L. Voz(5), Karen Hensen(5), Marleen M.R. Petit(5), Torik Ayoubi(5), Ilse G.L. Pauli(4), Koen Kas(4), Sandra Meulemans(4), Neil A. Taylor(3), Boudewijn Van Damme(3), Koenraad Devriendt(3), Caroline Braem(3), Jeroen Declercq(3), Frederik Van Dyck(3), Laurence Fiette(3), Nabil G. Seidah(3), Hans L. P. van Duijnhoven(2), Roland J. Siezen(2), E. Meyen(2)