Norman R. Klinman

Immunology and Microbiology · Life Sciences

50h-index7.8kcitations162works0.02yr avg
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Research Topics

T-cell and B-cell Immunology(101), Monoclonal and Polyclonal Antibodies Research(65), Immune Cell Function and Interaction(51), Immunotherapy and Immune Responses(39), Glycosylation and Glycoproteins Research(21)

Publications162 total

The mechanism of antigenic stimulation of primary and secondary clonal precursor cells. 1972.
PubMed·2005
When Two-Dimensional Structure Led the Way
The Journal of Immunology·2004
Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta.
PubMed·2003· 67 cited
Decreased Frequency of Somatic Hypermutation and Impaired Affinity Maturation but Intact Germinal Center Formation in Mice Expressing Antisense RNA to DNA Polymerase ζ
The Journal of Immunology·2001· 148 citedOpen Access
Evolution and the molecular basis of somatic hypermutation of antigen receptor genes
Philosophical Transactions of the Royal Society B Biological Sciences·2001· 28 citedOpen Access
Relative Roles of Somatic and Darwinian Evolution in Shaping the Antibody Response
Immunologic Research·2000· 13 cited
B Cell Maintenance in Aged Mice Reflects Both Increased B Cell Longevity and Decreased B Cell Generation
The Journal of Immunology·1999· 171 citedOpen Access
Pre-B cell receptor-mediated selection of pre-B cells synthesizing functional mu heavy chains.
PubMed·1998· 86 cited
Pre-B Cell Receptor-Mediated Selection of Pre-B Cells Synthesizing Functional μ Heavy Chains
The Journal of Immunology·1998· 82 citedOpen Access
Clonal Selection
Elsevier eBooks·1998
Repertoire Diversification of Primary vs Memory B Cell Subsets
Current topics in microbiology and immunology·1998· 3 cited
The B‐cell biology of aging
Immunological Reviews·1997· 91 cited
The cellular origins of memory B cells
Seminars in Immunology·1997· 21 cited
Introduction: B-cell memory
Seminars in Immunology·1997· 1 cited
Antigen-independent changes in naive CD4 T cells with aging.
The Journal of Experimental Medicine·1996· 258 citedOpen Access
The “Clonal Selection Hypothesis” and Current Concepts of B Cell Tolerance
Immunity·1996· 127 citedOpen Access
In Vitro Analysis of the Generation and Propagation of Memory B Cells
Immunological Reviews·1996· 18 cited
Phosphotyrosine‐dependent association between CD22 and protein tyrosine phosphatase 1C
European Journal of Immunology·1995· 116 cited
Heavy chain V gene-specific elimination of B cells during the pre-B cell to B cell transition.
The Journal of Immunology·1995· 36 cited
Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro
Immunity·1995· 55 citedOpen Access
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Frequent Co-authors

N H Sigal(6), Patricia J. Gearhart(5), Fred Karush(5), Debra J. Decker(4), Gregory H. Kline(4), Joan L. Press(4), P J Linton(3), Phyllis‐Jean Linton(3), Samantha Zaharevitz(3), Dorit Zharhary(3), John H. Rockey(3), Judy M. Teale(3), Linda A. Sherman(2), Marilyn Diaz(2), Laurent Verkoczy(2), Eleanor S. Metcalf(2), N E Boyle(2), Ulrike Keyna(2), Hans‐Martin Jäck(2), Susan K. Pierce(2)