Brian J. Fitzsimmons

California Institute of Technology — United States

Chemistry · Physical Sciences

25h-index1.6kcitations72works0.02yr avg
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Research Topics

Carbohydrate Chemistry and Synthesis(27), Synthetic Organic Chemistry Methods(11), Microbial Natural Products and Biosynthesis(9), Fluorine in Organic Chemistry(7), Click Chemistry and Applications(6)

Publications72 total

The Total Synthesis of the Enantiomer of Lasalocid A
CaltechTHESIS (California Institute of Technology)·2018Open Access
Avortement médical
Journal of Obstetrics and Gynaecology Canada·2016· 3 cited
Parametric and Molecular Structural Relationships of Dipeptides
The Journal of Physical Chemistry·1994
Justicidin E: A new leukotriene biosynthesis inhibitor.
Bioorganic & Medicinal Chemistry Letters·1993· 25 cited
Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase
Journal of Medicinal Chemistry·1992· 30 citedOpen Access
ChemInform Abstract: (4 + 2)Cycloaddition Reaction of Bis(trichloroethyl) Azodicarboxylate and Glycals: Preparation of a C1‐C1 2‐Amino Disaccharide.
ChemInform·1990
ChemInform Abstract: (4 + 2) Cycloaddition Reaction of Dibenzyl Azodicarboxylate and Glycals.
ChemInform·1989
ChemInform Abstract: Leukotrienes and Lipoxins: Synthesis and Biosynthesis
ChemInform·1989
ChemInform Abstract: The Lipoxins: Synthesis and Biosynthesis
ChemInform·1989
[4 + 2] Cycloaddition reaction of dibenzyl azodicarboxylate and glycals
Journal of the American Chemical Society·1989· 78 cited
[4+2] Cycloaddition reaction of bis (trichloroethyl) azodicarboxylate and glycals: preparation of a C1-C1 2-amino disaccharide
Tetrahedron Letters·1989· 45 cited
ChemInform Abstract: Preparation of Complex Aminoglycosides: A New Strategy.
ChemInform·1988
The in vivo production of peptide leukotrienes after pulmonary anaphylaxis in the rat.
The Journal of Immunology·1988· 24 citedOpen Access
Preparation of complex aminoglycosides: a new strategy
Journal of the American Chemical Society·1988· 45 cited
ChemInform Abstract: Synthesis of 5‐O‐Benzoyl‐14,15‐didehydroleukotriene B4 (LTB4) Ethyl Ester (Ia) and 5‐O‐Benzoyl‐14,15‐didehydro‐20‐hydroxyleukotriene B4 (LTB4) Ethyl Ester (Ib): Direct Precursors of Labeled LTB4s.
ChemInform·1988
Biochemical Studies on Mammalian Lipoxygenases<sup>a</sup>,<sup>b</sup>
Annals of the New York Academy of Sciences·1988· 24 cited
The dihydrooxadiazine approach to 2 amino sugars
1988
Lipoxin Syntheses by Arachidonate 12- and 5-Lipoxygenases Purified from Porcine Leukocytes
1988· 10 cited
The synthesis of 5-O-benzoyl-14,15-didehydro-leukotriene B4 (LTB4) ethyl ester and 5-O-benzoyl-14,15-didehydro-20-hydroxy-leukotriene B4 (LTB4) ethyl ester: The direct precursors of labelled LTB4's
The Journal of Organic Chemistry·1988· 20 cited
Lipoxygenase Inhibitors and Leukotriene Receptor Antagonists
1988· 1 cited
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Frequent Co-authors

Joshua Rokach(32), Yves Leblanc(12), Jillian F. Evans(9), Julian Adams(6), Y. LEBLANC(5), S. Charleson(5), Natsuo Ueda(5), Shozo Yamamoto(5), Bert Fraser‐Reid(5), Alan Brash(4), A. Foster(4), Robert E. Ireland(3), D J Nathaniel(3), Claire Leveillé(3), Anthony W. Ford‐Hutchinson(3), Chieko Yokoyama(3), Robert Zamboni(3), R. Badoud(2), Glenn J. McGarvey(2), Suvit Thaisrivongs(2)