Søren B. Jensen

Aarhus University — Denmark

Immunology and Microbiology · Life Sciences

16h-index4.9kcitations22works0.02yr avg
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Research Topics

interferon and immune responses(18), Immune Response and Inflammation(6), Inflammasome and immune disorders(5), Viral Infections and Vectors(5), RNA modifications and cancer(4)

Publications22 total

Author Correction: STEEP mediates STING ER exit and activation of signaling
Nature Immunology·2020· 7 citedOpen Access
STEEP mediates STING ER exit and activation of signaling
Nature Immunology·2020· 157 citedOpen Access
Cellular Requirements for Sensing and Elimination of Incoming HSV-1 DNA and Capsids
Journal of Interferon & Cytokine Research·2019· 23 cited
Attenuation of c <scp>GAS</scp> ‐ <scp>STING</scp> signaling is mediated by a p62/ <scp>SQSTM</scp> 1‐dependent autophagy pathway activated by TBK1
The EMBO Journal·2018· 452 citedOpen Access
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP
Nature Communications·2017· 283 citedOpen Access
<scp>HSV</scp> ‐1 <scp>ICP</scp> 27 targets the <scp>TBK</scp> 1‐activated STING signalsome to inhibit virus‐induced type I <scp>IFN</scp>  expression
The EMBO Journal·2016· 225 citedOpen Access
Interferon γ-inducible Protein (IFI) 16 Transcriptionally Regulates Type I Interferons and Other Interferon-stimulated Genes and Controls the Interferon Response to both DNA and RNA Viruses
Journal of Biological Chemistry·2014· 136 citedOpen Access
<i>Listeria monocytogenes</i> induces IFNβ expression through an IFI16‐, cGAS‐ and STING‐dependent pathway
The EMBO Journal·2014· 255 citedOpen Access
Sensing the hybrid--a novel PAMP for TLR9
The EMBO Journal·2014· 6 citedOpen Access
Correction for Jakobsen et al., IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
Proceedings of the National Academy of Sciences·2013Open Access
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
Proceedings of the National Academy of Sciences·2013· 332 citedOpen Access
Adenovirus-Based Vaccine against <i>Listeria monocytogenes</i>: Extending the Concept of Invariant Chain Linkage
The Journal of Immunology·2013· 29 cited
U20 inhibits death receptor and pattern-recognition receptor signaling in vitro, but increases inflammation in vivo
2013
Innate Immune recognition mechanisms: Herpes simplex Virus, an enveloped DNA virus
2013
Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING
Nature Immunology·2012· 235 citedOpen Access
Sensing of RNA Viruses: a Review of Innate Immune Receptors Involved in Recognizing RNA Virus Invasion
Journal of Virology·2012· 607 citedOpen Access
RNA Virus Invasion Recognizing Immune Receptors Involved in Sensing of RNA Viruses: a Review of Innate
2012
Activation of Autophagy by α-Herpesviruses in Myeloid Cells Is Mediated by Cytoplasmic Viral DNA through a Mechanism Dependent on Stimulator of IFN Genes
The Journal of Immunology·2011· 101 citedOpen Access
IFI16 is an innate immune sensor for intracellular DNA
Nature Immunology·2010· 1.6k citedOpen Access
RIG-I-mediated Activation of p38 MAPK Is Essential for Viral Induction of Interferon and Activation of Dendritic Cells
Journal of Biological Chemistry·2009· 118 citedOpen Access
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Frequent Co-authors

Søren R. Paludan(15), Thaneas Prabakaran(6), Martin R. Jakobsen(6), Katherine A. Fitzgerald(5), Rasmus O. Bak(5), Anders Laustsen(5), Kristy Horan(4), Chiranjeevi Bodda(4), Bao‐cun Zhang(4), Line S. Reinert(4), Christian K. Holm(4), Zhijian J. Chen(4), Tengchuan Jin(3), Allan Randrup Thomsen(3), Maria H. Christensen(3), Kathrine Hansen(3), Jacob Giehm Mikkelsen(3), Simon Rasmussen(3), Rune Hartmann(3), Shruti Sharma(2)