Lufen Chang

University of California San Diego — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index14.5kcitations34works0.02yr avg
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Research Topics

NF-κB Signaling Pathways(12), Cancer-related Molecular Pathways(10), Melanoma and MAPK Pathways(8), Cell death mechanisms and regulation(6), Cytokine Signaling Pathways and Interactions(5)

Publications34 total

Author Correction: A central role for JNK in obesity and insulin resistance
Nature·2023· 7 citedOpen Access
Adobe PDF - 0728_sup_tables_1-3,_sup_figs_1-3.pdf from p53R2 Inhibits the Proliferation of Human Cancer Cells in Association with Cell-Cycle Arrest
2023Open Access
Adobe PDF - 0728_sup_tables_1-3,_sup_figs_1-3.pdf from p53R2 Inhibits the Proliferation of Human Cancer Cells in Association with Cell-Cycle Arrest
2023Open Access
Data from p53R2 Inhibits the Proliferation of Human Cancer Cells in Association with Cell-Cycle Arrest
2023Open Access
Data from p53R2 Inhibits the Proliferation of Human Cancer Cells in Association with Cell-Cycle Arrest
2023Open Access
ITCH nuclear translocation and H1.2 polyubiquitination negatively regulate the DNA damage response
Nucleic Acids Research·2018· 27 citedOpen Access
Triptolide-Assisted Phosphorylation of p53 Suppresses Inflammation-Induced NF-κB Survival Pathways in Cancer Cells
Molecular and Cellular Biology·2017· 36 citedOpen Access
Chromosomal instability, inflammation, plasmacytic neoplasms, elevated stem cell antigen 1 expression in mice deficient in Rrm2b gene
Journal of Blood Disorders & Transfusion·2014
Chromosomal Instability Triggered by Rrm2b Loss Leads to IL-6 Secretion and Plasmacytic Neoplasms
Cell Reports·2013· 27 citedOpen Access
MicroRNA-657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin-like enhancer protein 1 through nuclear factor kappa B pathways
Hepatology·2012· 67 citedOpen Access
RRM2B Suppresses Activation of the Oxidative Stress Pathway and is Up-regulated by P53 During Senescence
Scientific Reports·2012· 44 citedOpen Access
Canonical Nuclear Factor κB Pathway Links Tumorigenesis of Synchronous Mantle-Cell Lymphoma, Clear-Cell Renal-Cell Carcinoma, and GI Stromal Tumor
Journal of Clinical Oncology·2011· 7 citedOpen Access
p53R2 Inhibits the Proliferation of Human Cancer Cells in Association with Cell-Cycle Arrest
Molecular Cancer Therapeutics·2011· 46 citedOpen Access
ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage
Proceedings of the National Academy of Sciences·2008· 61 citedOpen Access
Functional <i>in vivo</i> interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
Proceedings of the National Academy of Sciences·2006· 342 citedOpen Access
Loss of hepatic NF-κB activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation
Proceedings of the National Academy of Sciences·2006· 403 citedOpen Access
The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover
Cell·2006· 687 citedOpen Access
632. Sustained Function and Enhanced Replicative Capacity of Anti-Tumor CD4+ Effectors by Enforced Co-Stimulation
Molecular Therapy·2006Open Access
Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases
Cell·2005· 1.8k citedOpen Access
Essential Roles of Receptor-Interacting Protein and TRAF2 in Oxidative Stress-Induced Cell Death
Molecular and Cellular Biology·2004· 143 citedOpen Access
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Frequent Co-authors

Michael Karin(15), Yun Yen(10), Xiyong Liu(7), Bingsen Zhou(6), Xiwei Wu(6), Mei-Ling Kuo(6), David K. Ann(6), Keqiang Zhang(5), Yan Wang(5), Shin Maeda(4), Zuoning Han(4), Gary S. Firestein(4), Jun Wu(4), N. Zhou(4), Jiro Hirosumi(3), Gürol Tuncman(3), Gökhan S. Hotamışlıgil(3), David L. Boyle(3), Brydon L. Bennett(3), Robin Guo(3)