Eric S. Marr

Medicine · Health Sciences

16h-index1.8kcitations41works0.02yr avg
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Research Topics

HER2/EGFR in Cancer Research(8), Phosphodiesterase function and regulation(8), RNA and protein synthesis mechanisms(4), Cell Adhesion Molecules Research(4), Receptor Mechanisms and Signaling(4)

Publications41 total

Data from Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271
2023Open Access
Supplementary Data from Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271
2023Open Access
Data from Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271
2023Open Access
Supplementary Data from Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271
2023Open Access
Author Correction: Dopamine D3 receptor antagonist reveals a cryptic pocket in aminergic GPCRs
Scientific Reports·2019Open Access
Dopamine D3 receptor antagonist reveals a cryptic pocket in aminergic GPCRs
Scientific Reports·2018· 53 citedOpen Access
Discovery and Characterization of a Novel Dihydroisoxazole Class of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) Receptor Potentiators
Journal of Medicinal Chemistry·2013· 22 cited
Pyridone-Conjugated Monobactam Antibiotics with Gram-Negative Activity
Journal of Medicinal Chemistry·2013· 63 cited
Crystal structure of P.aeruginosa PBP3 in complex with compound 4
2013
Crystal structures of interleukin 17A and its complex with IL-17 receptor A
Nature Communications·2013· 140 citedOpen Access
Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates
Bioorganic & Medicinal Chemistry Letters·2013· 21 cited
Crystal structure of compound 4d bound to large ribosomal subunit (50S) from Deinococcus radiodurans
2013
Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion
Journal of Biological Chemistry·2011· 5 citedOpen Access
Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 2
2011
Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia
Journal of Medicinal Chemistry·2011· 52 citedOpen Access
Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of<i>Pseudomonas aeruginosa</i>
Proceedings of the National Academy of Sciences·2010· 159 citedOpen Access
Design, synthesis, structure-activity relationships, and biological evaluation of AMPA positive allosteric modulators (PAMs)
Abstracts of papers - American Chemical Society·2010
Abstract A86: Design, synthesis, and SAR of focal adhesion kinase (FAK) inhibitors
Molecular Cancer Therapeutics·2009· 2 cited
Identification of a Brain Penetrant PDE9A Inhibitor Utilizing Prospective Design and Chemical Enablement as a Rapid Lead Optimization Strategy
Journal of Medicinal Chemistry·2009· 65 citedOpen Access
A systematic study of 50S ribosomal subunit purification enabling robust crystallization
Acta Crystallographica Section D Biological Crystallography·2009· 14 cited
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Frequent Co-authors

Jayvardhan Pandit(13), F.F. Vajdos(10), Catherine A. Hulford(9), W. Gregory Roberts(8), Ethan Ung(8), Pamela Whalen(8), John C. Kath(8), Michael J. Luzzio(8), Nandini C. Patel(8), Seungil Han(8), Luis Martinez-Alsina(7), Marianne Lorenzen(7), Martin A. Berliner(7), Susan LaGreca(7), Jitesh P. Jani(7), Matt Griffor(7), Christofer Autry(6), Earling Emerson(6), Peter K. LeMotte(6), Xinjun Hou(6)