Traci M. Tanaka Hall

National Institutes of Health — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

35h-index5.4kcitations125works0.42yr avg
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Research Topics

RNA Research and Splicing(61), RNA and protein synthesis mechanisms(56), RNA modifications and cancer(55), RNA Interference and Gene Delivery(9), RNA regulation and disease(8)

Publications125 total

Human Pumilio proteins use fuzzy multivalent hydrophobic interactions to recruit the CCR4–NOT deadenylase complex to repress mRNAs
2025Open Access
Crystal structures of <i>Caenorhabditis elegans</i> PUF-3 depict plasticity of RNA recognition that enables germline gene regulation
Nucleic Acids Research·2025Open Access
The DND1–NANOS3 complex shapes the primordial germ cell transcriptome via a heptanucleotide sequence in mRNA 3′ UTRs
2025Open Access
<i>C. elegans</i> FBF-1 and FBF-2 C-terminal intrinsically-disordered regions differentially regulate RNA-binding affinity
RNA·2025Open Access
A higher order PUF complex is central to regulation of C. elegans germline stem cells
Nature Communications·2025· 1 citedOpen Access
The TRIM-NHL RNA-binding protein Brain Tumor coordinately regulates expression of the glycolytic pathway and vacuolar ATPase complex
Nucleic Acids Research·2024· 1 citedOpen Access
A higher order PUF complex is central to regulation of <i>C. elegans</i> germline stem cells
2024· 1 citedOpen Access
Intra- and inter-molecular regulation by intrinsically-disordered regions governs PUF protein RNA binding
Nature Communications·2023· 13 citedOpen Access
The translational repressor Glorund uses interchangeable RNA recognition domains to recognize Drosophila <i>nanos</i>
Nucleic Acids Research·2023· 1 citedOpen Access
Abstract 6101: PUM3 is a novel R-loop regulator and is essential for efficient DNA damage repair
Cancer Research·2023
Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB
Molecular Cell·2022· 54 citedOpen Access
High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP
Journal of Biological Chemistry·2022· 6 citedOpen Access
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB
2022· 4 citedOpen Access
Bipartite interaction sites differentially modulate RNA-binding affinity of a protein complex essential for germline stem cell self-renewal
Nucleic Acids Research·2021· 9 citedOpen Access
Faculty Opinions recommendation of Structure and mechanistic features of the prokaryotic minimal RNase P.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2021
Faculty Opinions recommendation of Minimal protein-only RNase P structure reveals insights into tRNA precursor recognition and catalysis.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2021
Specific and Modular Binding Code for Cytosine Recognition in Pumilio/FBF (PUF) RNA-binding Domains
UNC Libraries·2020· 5 citedOpen Access
Engineering splicing factors with designed specificities
UNC Libraries·2020· 2 citedOpen Access
Engineered proteins with Pumilio/ fem-3 mRNA binding factor scaffold to manipulate RNA metabolism
UNC Libraries·2020Open Access
Pentatricopeptide repeats of protein-only RNase P use a distinct mode to recognize conserved bases and structural elements of pre-tRNA
Nucleic Acids Research·2020· 35 citedOpen Access
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Frequent Co-authors

Chen Qiu(11), Marvin Wickens(8), Zachary T. Campbell(7), Yeming Wang(5), Kathleen L. McCann(5), Jun Zhang(5), Phillip D. Zamore(4), Aaron C. Goldstrohm(4), Xiaoqiang Wang(3), Jeffery A. Porter(3), Philip A. Beachy(3), Daniel J. Leahy(3), Robert Dutcher(3), Yang Wang(3), Zefeng Wang(3), Gang Lu(3), Chase A. Weidmann(3), Robert N. Wine(3), Susan J. Baserga(3), Takamasa Teramoto(3)