Iulian I. Oprea

Stony Brook School — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index815citations21works1.02yr avg
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Research Topics

RNA Interference and Gene Delivery(10), Advanced biosensing and bioanalysis techniques(7), Virus-based gene therapy research(5), DNA and Nucleic Acid Chemistry(3), Bacteriophages and microbial interactions(3)

Publications21 total

Cholinergic tone abnormalities and relationships with smoking severity in human cigarette smokers: exploratory positron emission tomography study using [18F]VAT
Molecular Psychiatry·2025· 1 cited
A New Relantioship for the Prediction of the Formation of Gas Hydrate in Fluids Petroleum
Journal of Energy Research and Reviews·2023· 1 citedOpen Access
Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes
Oncogene·2017· 32 citedOpen Access
Progresses towards safe and efficient gene therapy vectors
Oncotarget·2015· 212 citedOpen Access
A murine model of acute myeloid leukemia with<i>Evi1</i>overexpression and autocrine stimulation by an intracellular form of GM-CSF in DA-3 cells
Leukemia & lymphoma/Leukemia and lymphoma·2015· 2 cited
PO4-7: Functional selectivity of the insulin-like growth factor type 1 receptor (IGF-1R) signaling: therapeutic implications for cancer treatment
Growth Hormone & IGF Research·2014
Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression
Molecular Therapy — Nucleic Acids·2014· 3 citedOpen Access
Novel mechanisms of regulation of IGF-1R action: functional and therapeutic implications.
PubMed·2013· 21 cited
Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA
Nucleic Acids Research·2013· 30 citedOpen Access
β-Arrestin–biased agonism as the central mechanism of action for insulin-like growth factor 1 receptor–targeting antibodies in Ewing’s sarcoma
Proceedings of the National Academy of Sciences·2012· 65 citedOpen Access
P03-8 Tumorigenicity of Ewing's sarcoma cells is dependent on the level of beta-arrestin 1
Growth Hormone & IGF Research·2012
P3.41. Clinical and genetic findings in a large cohort of patients with congenital myopathies due to mutations in the skeletal muscle ryanodine receptor (RYR1) gene
Neuromuscular Disorders·2011
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo
Nucleic Acids Research·2011· 296 citedOpen Access
Optimizing anti-gene oligonucleotide ‘Zorro-LNA’ for improved strand invasion into duplex DNA
Nucleic Acids Research·2010· 34 citedOpen Access
Non-viral nanovectors for gene delivery: factors that govern successful therapeutics
Expert Opinion on Drug Delivery·2010· 52 cited
Temperature-Assisted Cyclic Hybridization (TACH): An Improved Method for Supercoiled DNA Hybridization
Molecular Biotechnology·2010· 1 cited
Fatty acid–spermine conjugates as DNA carriers for nonviral in vivo gene delivery
Gene Therapy·2009· 22 cited
Nanotechnology approaches for gene transfer
Genetica·2009· 22 cited
Use of protein markers for the calculation of the coefficient of similarity in hybridization of Serbian spruce (Picea omorika/Panc./Purkyne).
Lucrările sesiunii ştiinţifice bienale cu participare internaţională Pădurea şi Dezvoltarea Durabilă Braşov, Romania, 27-28 octombrie 2006.·2007
Increased stability and specificity through combined hybridization of peptide nucleic acid (PNA) and locked nucleic acid (LNA) to supercoiled plasmids for PNA-anchored “Bioplex” formation
Biomolecular Engineering·2005· 21 cited
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Frequent Co-authors

Smith Rjh(10), Pedro M. D. Moreno(9), Karin E. Lundin(7), Oscar E. Simonson(6), Leonard Girnita(6), Joana R. Viola(5), Claire Worrall(5), Samir EL Andaloussi(4), Eman M. Zaghloul(4), Ada Girnita(3), Naida Suleymanova(3), George A. Călin(2), Burcu Bestas(2), Erik B. Pedersen(2), Jesper Wengel(2), Caitrin Crudden(2), Mathias G. Svahn(2), Daniela Nedelcu(2), Taavi Lehto(1), Imre Mäger(1)