Christopher J. Halbrook

University of California, Irvine — United States

Medicine · Health Sciences

28h-index6.6kcitations141works1.12yr avg
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Research Topics

Pancreatic and Hepatic Oncology Research(89), Epigenetics and DNA Methylation(43), Cancer, Hypoxia, and Metabolism(25), Hedgehog Signaling Pathway Studies(20), Cancer Immunotherapy and Biomarkers(19)

Publications141 total

Interfacial Tension Modulates Viscous Microfluidic Droplet Generation
2025Open Access
Abstract A016: Defining UHRF1 as a crucial factor in pancreatic cancer progression and treatment
Cancer Research·2025
Abstract A055: Targeting myeloid metabolism to remodel the pancreatic tumor immune microenvironment
Cancer Research·2025
Mevalonate Biosynthesis is a Metabolic Vulnerability of Gemcitabine-resistant Pancreatic Cancer
2025Open Access
Exploiting TGF-β-mediated Stromal Programming in Homologous Recombination-Deficient Pancreatic Cancer
2025Open Access
Comparative Analysis of Primary and Liver Fibroblasts Reveals MET as a Potent Target in Pancreatic Cancer Metastasis
2025Open Access
Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer
2025Open Access
Homologous Repair‐Deficient Pancreatic Cancer: Refined Targeting of DNA Damage Response is an Effective Therapeutic Strategy
United European Gastroenterology Journal·2025Open Access
Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes
EMBO Reports·2025· 3 citedOpen Access
Abstract LB454: Targeting the epithelial-stromal cell crosstalk in metastatic pancreatic cancer
Cancer Research·2025
Abstract LB053: Targeting macrophage metabolism in pancreatic cancer
Cancer Research·2025
A novel DNA repair protein, N-Myc downstream regulated gene 1 (NDRG1), links stromal tumour microenvironment to chemoresistance
2025· 4 citedOpen Access
CARMIL1-AA selectively inhibits macropinocytosis while sparing autophagy
Molecular Biology of the Cell·2024· 5 citedOpen Access
Abstract C052: Repurposing Statins to Target Gemcitabine Resistance in Pancreatic Cancer
Cancer Research·2024
Abstract C045: Targeting metabolic heterogeneity in pancreatic ductal adenocarcinoma
Cancer Research·2024Open Access
Abstract A055: Multiomics profiling reveals druggable tumor-stroma interactions in ATM-deficient pancreatic cancer
Cancer Research·2024
Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung
2024Open Access
Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions
PLoS ONE·2024· 4 citedOpen Access
Cancer Hallmarks: Piecing the Puzzle Together
Cancer Discovery·2024· 11 citedOpen Access
Abstract 4441: The epigenetic factor BMI1 regulates metabolism and tumorigenesis in human pancreatic cancer cells
Cancer Research·2024
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Frequent Co-authors

Costas A. Lyssiotis(37), Marina Pasca di Magliano(23), Howard C. Crawford(22), Li Zhang(14), Barbara Scott Nelson(13), Zeribe C. Nwosu(13), Peter Sajjakulnukit(12), Yaqing Zhang(11), Daniel M. Kremer(10), Eileen S. Carpenter(10), Ho‐Joon Lee(9), Galloway Thurston(7), Samantha B. Kemp(7), Nina G. Steele(7), Anthony Andren(7), Timothy L. Frankel(6), Filip Bednar(6), Carlos E. Espinoza(6), Samuel A. Kerk(6), Haoqiang Ying(5)