Rumiko Moriguchi

Hokkaido University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index999citations12works0.02yr avg
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Research Topics

RNA Interference and Gene Delivery(12), Advanced biosensing and bioanalysis techniques(8), Immunotherapy and Immune Responses(6), Virus-based gene therapy research(6), Lipid Membrane Structure and Behavior(1)

Publications12 total

Octaarginine-Modified Liposomes Enhance Cross-Presentation by Promoting the C-Terminal Trimming of Antigen Peptide
Molecular Pharmaceutics·2014· 30 cited
Incorporation of polyinosine–polycytidylic acid enhances cytotoxic T cell activity and antitumor effects by octaarginine-modified liposomes encapsulating antigen, but not by octaarginine-modified antigen complex
International Journal of Pharmaceutics·2012· 36 cited
Reprint of: Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation
Journal of Controlled Release·2010· 23 cited
Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation☆
Journal of Controlled Release·2010· 161 cited
Multi-layered nanoparticles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process
Biomaterials·2009· 139 cited
Non-linear pharmacodynamics in the transfection efficiency of a non-viral gene delivery system
International Journal of Pharmaceutics·2008· 13 cited
Efficient MHC Class I Presentation by Controlled Intracellular Trafficking of Antigens in Octaarginine-modified Liposomes
Molecular Therapy·2008· 106 citedOpen Access
An artificial virus-like nano carrier system: enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives
Analytical and Bioanalytical Chemistry·2008· 115 cited
Delivery of Condensed DNA by Liposomal Non-viral Gene Delivery System into Nucleus of Dendritic Cells
Biological and Pharmaceutical Bulletin·2006· 32 citedOpen Access
Non-linear pharmacodynamics in a non-viral gene delivery system: Positive non-linear relationship between dose and transfection efficiency
Journal of Controlled Release·2005· 40 cited
A multifunctional envelope-type nano device for novel gene delivery of siRNA plasmids
International Journal of Pharmaceutics·2005· 71 cited
Development of a non-viral multifunctional envelope-type nano device by a novel lipid film hydration method
Journal of Controlled Release·2004· 233 cited

Frequent Co-authors

Kentaro Kogure(12), Hideyoshi Harashima(11), Shiroh Futaki(6), Hidetaka Akita(6), Takashi Nakamura(6), Yoshio Nakamura(3), Kentaro Sasaki(2), Masaharu Ueno(2), Tomoko Higashi(2), Satoshi Serada(2), Minoru Fujimoto(2), Tetsuji Naka(2), Arisa Minoura(2), Tomoya Masuda(2), Radostin Danev(2), Kuniaki Nagayama(2), Hirofumi Hamada(2), Asako Kudo(1), Masaya Yamaguti(1), Ikramy A. Khalil(1)