Maria Jakobsen

Aarhus University — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index929citations18works3.02yr avg
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Research Topics

RNA Interference and Gene Delivery(8), Virus-based gene therapy research(6), Immunotherapy and Immune Responses(3), CRISPR and Genetic Engineering(3), Inflammasome and immune disorders(2)

Publications18 total

STING signals to NF-κB from late endolysosomal compartments using IRF3 as an adaptor
Nature Immunology·2025· 6 cited
Genetically heterozygous - transcriptionally homozygous IRF7 deficiency underlies herpesvirus CNS infections in humans
The Journal of Experimental Medicine·2025
Imaging Rheumatoid Arthritis in Mice Using Combined Near Infrared and 19F Magnetic Resonance Modalities
Scientific Reports·2019· 21 citedOpen Access
Lipidoid-siRNA Nanoparticle-Mediated IL-1β Gene Silencing for Systemic Arthritis Therapy in a Mouse Model
Molecular Therapy·2019· 63 citedOpen Access
Theranostic Niosomes for Efficient siRNA/MicroRNA Delivery and Activatable Near-Infrared Fluorescent Tracking of Stem Cells
ACS Applied Materials & Interfaces·2018· 56 cited
Impact of PEG Chain Length on the Physical Properties and Bioactivity of PEGylated Chitosan/siRNA Nanoparticles in Vitro and in Vivo
ACS Applied Materials & Interfaces·2017· 133 cited
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP
Nature Communications·2017· 283 citedOpen Access
Robust Lentiviral Gene Delivery But Limited Transduction Capacity of Commonly Used Adeno-Associated Viral Serotypes in Xenotransplanted Human Skin
Human Gene Therapy Methods·2015· 6 cited
A Novel Homologous Model for Gene Therapy of Dwarfism by Non-Viral Transfer of the Mouse Growth Hormone Gene into Immunocompetent Dwarf Mice
Current Gene Therapy·2014· 12 cited
Myoblasts generated by lentiviral mediated MyoD transduction of myotonic dystrophy type 1 (DM1) fibroblasts can be used for assays of therapeutic molecules
BMC Research Notes·2011· 25 citedOpen Access
Targeting of human interleukin-12B by small hairpin RNAs in xenografted psoriatic skin
BMC Dermatology·2011· 22 citedOpen Access
An update on targeted gene repair in mammalian cells: methods and mechanisms
Journal of Biomedical Science·2011· 54 citedOpen Access
Social effects of the educational revolution in Qatar: a gender perspective
Bergen Open Research Archive (BORA) (University of Bergen)·2010· 1 citedOpen Access
Amelioration of Psoriasis by Anti-TNF-α RNAi in the Xenograft Transplantation Model
Molecular Therapy·2009· 74 citedOpen Access
Hybrid Lentivirus-transposon Vectors With a Random Integration Profile in Human Cells
Molecular Therapy·2009· 97 citedOpen Access
Genomic insertion of lentiviral DNA circles directed by the yeast Flp recombinase
BMC Biotechnology·2008· 43 citedOpen Access
Characterization of transgenic mice with the expression of phenylalanine hydroxylase and GTP cyclohydrolase I in the skin
Experimental Dermatology·2005· 6 cited
Human breast cancer cells induce angiogenesis, recruitment, and activation of osteoclasts in osteolytic metastasis
Journal of Cancer Research and Clinical Oncology·2000· 27 citedOpen Access

Frequent Co-authors

Jacob Giehm Mikkelsen(8), Thomas G. Jensen(7), Frederik Dagnæs‐Hansen(6), Jørgen Kjems(4), Brian Moldt(4), Søren R. Paludan(3), Chuanxu Yang(3), Karin Stenderup(3), Cecilia Rosada(3), Ping Song(3), Nicklas Heine Staunstrup(2), Søren Kamp(2), Tomas Norman Dam(2), Thomas J. Corydon(2), Rasmus O. Bak(2), Lars Aagaard(2), Ryo Narita(2), Morten Kelder Skouboe(2), Trine H. Mogensen(2), Kasper L. Jønsson(1)