Timothy Davis

University of Colorado Anschutz Medical Campus — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index1.5kcitations26works0.02yr avg
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Research Topics

CRISPR and Genetic Engineering(12), RNA and protein synthesis mechanisms(4), Virus-based gene therapy research(4), Occupational and environmental lung diseases(4), CAR-T cell therapy research(3)

Publications26 total

Comprehensive analysis and accurate quantification of unintended large gene modifications induced by CRISPR-Cas9 gene editing
Science Advances·2022· 77 citedOpen Access
Circulating CD8 <sup>+</sup> mucosal‐associated invariant T cells correlate with improved treatment responses and overall survival in anti‐PD‐1‐treated melanoma patients
Clinical & Translational Immunology·2022· 24 citedOpen Access
Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus
Molecular Therapy·2021· 63 citedOpen Access
Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation correction in the endogenous locus
2021· 8 citedOpen Access
Gene Therapy: Introduction
International Journal of Clinical Skills·2021
Tools for experimental and computational analyses of off-target editing by programmable nucleases
Nature Protocols·2020· 94 citedOpen Access
Circulating CD8+ MAIT cells correlate with improved outcomes in anti-PD1 treated melanoma patients
2020· 1 citedOpen Access
AAV-CRISPR Gene Editing Is Negated by Pre-existing Immunity to Cas9
Molecular Therapy·2020· 217 citedOpen Access
Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease
Nucleic Acids Research·2019· 149 citedOpen Access
Highly Efficient Editing of the Beta-Globin Gene in Patient Derived Hematopoietic Stem and Progenitor Cells to Treat Sickle Cell Disease
Blood·2018· 6 cited
PAR volume 145 issue 1 Cover and Back matter
Parasitology·2018Open Access
CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies
Blood·2017· 445 citedOpen Access
Examination of CRISPR/Cas9 design tools and the effect of target site accessibility on Cas9 activity
Experimental Physiology·2017· 27 citedOpen Access
Design and Validation of CRISPR/Cas9 Systems for Targeted Gene Modification in Induced Pluripotent Stem Cells
Methods in molecular biology·2016· 6 cited
PS1 - 170 Bmi1 is a Therapeutic Target in Recurrent Childhood Medulloblastoma
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques·2016Open Access
Abstract 2948: Glucose-6-phosphate dehydrogenase mediates drug resistance in diffuse large B-cell lymphoma
Cancer Research·2016
131. Chromatin-Dependent Loci Accessibility Affects CRISPR-Cas9 Targeting Efficiency
Molecular Therapy·2016· 1 citedOpen Access
Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome
Molecular Therapy·2015· 253 citedOpen Access
Environmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus
Genomics·2014· 56 citedOpen Access
Effect of EGFRvIII-targeted vaccine (CDX-110) on immune response and TTP when given with simultaneous standard and continuous temozolomide in patients with GBM
Journal of Clinical Oncology·2008· 46 cited
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Frequent Co-authors

Gang Bao(12), Ciaran M. Lee(11), Matthew H. Porteus(4), M.J. Garlepp(4), Bruce Robinson(4), T.I. Christmas(3), Steven E. Mutsaers(3), So Hyun Park(2), Daniel P. Dever(2), Joab Camarena(2), Yankai Zhang(2), Vivien Sheehan(2), Yidan Pan(2), Harshavardhan Deshmukh(2), Sriram Vaidyanathan(2), Ron Baik(2), Lü Chen(2), Dawn T. Bravo(2), Carlos J. Suarez(2), Shayda M. Abazari(2)