Joab Camarena

California Institute for Regenerative Medicine — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index3.9kcitations35works4.32yr avg
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Research Topics

CRISPR and Genetic Engineering(33), Hemoglobinopathies and Related Disorders(10), Virus-based gene therapy research(7), RNA Interference and Gene Delivery(7), Mosquito-borne diseases and control(5)

Publications35 total

Secreted Particle Information Transfer (SPIT) – A Cellular Platform for In Vivo Genetic Engineering
2024· 1 citedOpen Access
Enhancement of erythropoietic output by Cas9-mediated insertion of a natural variant in haematopoietic stem and progenitor cells
Nature Biomedical Engineering·2024· 8 citedOpen Access
Secreted Particle Information Transfer (SPIT) – A Cellular Platform for <i>In Vivo</i> Genetic Engineering
2024· 4 citedOpen Access
Using Human Genetics to Develop Strategies to Increase Erythropoietic Output from Genome-Edited Hematopoietic Stem and Progenitor Cells
Blood·2023Open Access
Demographic and socioeconomic disparities in receipt of ophthalmology consultation for facial trauma
BMJ Open Ophthalmology·2023· 3 citedOpen Access
Using human genetics to develop strategies to increase erythropoietic output from genome-edited hematopoietic stem and progenitor cells
2023· 5 citedOpen Access
3017 – ESTABLISHMENT OF A PLATFORM FOR EX VIVO GENE EDITING IN MULTIPOTENT HEMATOPOIETIC STEM CELLS
Experimental Hematology·2021
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease
Science Translational Medicine·2021· 150 citedOpen Access
Clinically relevant gene editing in hematopoietic stem cells for the treatment of pyruvate kinase deficiency
Molecular Therapy — Methods & Clinical Development·2021· 24 citedOpen Access
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells
Nature Medicine·2021· 80 citedOpen Access
Cas9-AAV6 gene correction of beta-globin in autologous HSCs improves sickle cell disease erythropoiesis in mice
Nature Communications·2021· 97 citedOpen Access
The TRACE-Seq method tracks recombination alleles and identifies clonal reconstitution dynamics of gene targeted human hematopoietic stem cells
Nature Communications·2021· 29 citedOpen Access
Clinically Relevant Gene Editing in Hematopoietic Stem Cells for the Treatment of Pyruvate Kinase Deficiency Hemolytic Anemia
2021Open Access
Correction of the Energetic Defects in Pyruvate Kinase Deficiency through Genome Editing in Hematopoietic Stem and Progenitor Cells
Blood·2020
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells
2020· 3 citedOpen Access
Cas9-AAV6 Gene Correction of Beta-Globin in Autologous HSCs Improves Sickle Cell Disease Erythropoiesis in Mice
2020· 12 citedOpen Access
3042 – CAS9-AAV6 GENE CORRECTION OF AUTOLOGOUS HSCS IMPROVES SICKLE CELL DISEASE ERYTHROPOIESIS IN MICE
Experimental Hematology·2020
TRACE-Seq Reveals Clonal Reconstitution Dynamics of Gene Targeted Human Hematopoietic Stem Cells
2020· 3 citedOpen Access
Cas9-AAV6-engineered human mesenchymal stromal cells improved cutaneous wound healing in diabetic mice
Nature Communications·2020· 77 citedOpen Access
Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease
Nucleic Acids Research·2019· 149 citedOpen Access
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Frequent Co-authors

Matthew H. Porteus(32), Daniel P. Dever(28), Carsten T. Charlesworth(14), Rasmus O. Bak(13), M. Kyle Cromer(10), Mark A. Behlke(7), Ravindra Majeti(7), Ciaran M. Lee(7), Gang Bao(7), Christopher A. Vakulskas(6), Renata M. Martin(6), Hiromitsu Nakauchi(6), Vivien Sheehan(6), Sruthi Mantri(5), Mara Pavel-Dinu(5), Kenneth I. Weinberg(5), Nobuko Uchida(5), Waracharee Srifa(5), Viktor T. Lemgart(4), Benjamin J. Lesch(4)