Jonas Demeulemeester

The Francis Crick Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

56h-index24.3kcitations267works7.82yr avg
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Research Topics

Cancer Genomics and Diagnostics(84), HIV Research and Treatment(51), HIV/AIDS drug development and treatment(49), RNA modifications and cancer(22), Chronic Lymphocytic Leukemia Research(15)

Publications202 total

Optical Genome Mapping Is a Powerful Diagnostic Tool in Non-Hodgkin Lymphoma
Modern Pathology·2025Open Access
ctDNA detectability and representativeness in seven body liquids from patients with metastatic breast cancer
Nature Communications·2025Open Access
Profiling the genomic landscape and evolutionary history of polyploid giant cancer cells in undifferentiated pleomorphic sarcomas
Cancer Letters·2025· 1 citedOpen Access
Single-cell mapping of alternative splicing linked to checkpoint immunotherapy response
Nucleic Acids Research·2025Open Access
Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data
Nature Communications·2025· 2 citedOpen Access
Emerging insights into mosaic errors of immunity
Trends in Immunology·2025Open Access
Long-read single-cell genome, transcriptome and open chromatin profiling links genotype to phenotypes
2025Open Access
An optimised computational approach for the identification of somatic structural variants in cancer
2025· 1 citedOpen Access
MYC-induced oncogenesis is dependent on acidic patches within its N-terminal intrinsically disordered domain
2025
Long-read single-cell genome, transcriptome and open chromatin profiling links genotype to phenotypes. v1
2025Open Access
Abstract 4094: Allosteric chromatin activity transition mechanisms drive epigenetic dosage compensation in essential genes triggered by oncogene activation in TRACERx
Cancer Research·2025
Abstract 7177: Deep genomic analysis of undifferentiated sarcoma
Cancer Research·2025
Single-cell genome and transcriptome sequencing without upfront whole-genome amplification reveals cell state plasticity of melanoma subclones
Nucleic Acids Research·2025· 6 citedOpen Access
Single-cell somatic copy number variants in brain using different amplification methods and reference genomes
Communications Biology·2024· 8 citedOpen Access
121P DNA methylation co-operates with genomic alterations during non-small cell lung cancer evolution
ESMO Open·2024Open Access
Focal deletions of a promoter tether activate the <i>IRX3</i> oncogene in T-cell acute lymphoblastic leukemia
Blood·2024· 5 citedOpen Access
Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction
Nature Biotechnology·2024· 5 citedOpen Access
Abstract 4340: Profiling the evolutionary history of giant cancer cells in sarcomas: Hopeful monsters or an evolutionary dead end
Cancer Research·2024
Abstract 1611: DNA methylation co-operates with genomic alterations during non-small cell lung cancer evolution
Cancer Research·2024
Abstract 2268: CREDAC: Copy number-based reference-free expression deconvolution analysis of cancers
Cancer Research·2024
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Frequent Co-authors

Zeger Debyser(24), Peter Van Loo(20), Frauke Christ(17), Jan De Rijck(13), Stefan C. Dentro(11), Maxime Tarabichi(11), Kerstin Haase(11), Moritz Gerstung(10), Clemency Jolly(10), Ignaty Leshchiner(10), Kortine Kleinheinz(10), Geoff Macintyre(10), Dimitri Livitz(10), Paul C. Boutros(10), Gad Getz(10), Marcin Imieliński(10), Florian Markowetz(10), Rik Gijsbers(10), Daniel Rosebrock(9), Yulia Rubanova(9)