Rik Gijsbers

Advanced Pharma — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

50h-index7.3kcitations327works6.02yr avg
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Research Topics

Virus-based gene therapy research(93), HIV Research and Treatment(70), HIV/AIDS drug development and treatment(54), CRISPR and Genetic Engineering(37), RNA Interference and Gene Delivery(30)

Publications326 total

Impact of rAAV-shRNA treatment targeting mechanosensitive Ilk1 and Fermt2 in a mouse model of sepsis-induced muscle weakness
PLoS ONE·2025Open Access
An Isogenic Human Myoblast Cell Model for Cystinosis Myopathy Reveals Alteration of Key Myogenic Regulatory Proteins
Journal of Cachexia Sarcopenia and Muscle·2025Open Access
From injury to recovery: functional neuronal regeneration after traumatic brain injury in the telencephalon of the young adult killifish
2025· 1 citedOpen Access
Trojan Horse-Like Vehicles for CRISPR-Cas Delivery: Engineering Extracellular Vesicles and Virus-Like Particles for Precision Gene Editing in Cystic Fibrosis
Human Gene Therapy·2025· 4 citedOpen Access
Downregulation of the Vasopressin-AQP2 Pathway Explains Secondary Nephrogenic Diabetes Insipidus Associated with Cystinosis: In Vivo and In Vitro Evidence
Journal of the American Society of Nephrology·2024
Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells
Cell Reports Medicine·2024· 48 citedOpen Access
Residual Cystine Transport Activity for Specific Infantile and Juvenile CTNS Mutations in a PTEC-Based Addback Model
Cells·2024· 1 citedOpen Access
An In Vitro Study of Virus-Like Particle Mediated CRISPR Gene Editing to Support Gene Modulation in the Human Ex Vivo Lung
The Journal of Heart and Lung Transplantation·2024Open Access
<i>MFSD12</i> depletion reduces cystine accumulation without improvement in proximal tubular function in experimental models for cystinosis
American Journal of Physiology-Renal Physiology·2024· 3 citedOpen Access
Current Status and Prospects of Viral Vector-Based Gene Therapy to Treat Kidney Diseases
Human Gene Therapy·2024· 3 citedOpen Access
Evaluation of the efficacy of cystinosin supplementation through CTNS mRNA delivery in experimental models for cystinosis
Scientific Reports·2023· 10 citedOpen Access
A Novel Renal Collecting Duct Model to Study Secondary Nephrogenic Diabetes Insipidus Associated with Cystinosis
Journal of the American Society of Nephrology·2023
Recombinant adeno-associated viral vector 2/8 model of il6 mediated chronic inflammation
European Heart Journal·2023Open Access
Tailoring stimuli-responsive PVDF-based copolymer membrane with engineered pore structure for efficient antibody purification
Chemical Engineering Journal·2023· 20 cited
Abstract P3059: Recombinant Adeno-associated Viral Vector 2/8 Model Of Interleukin 6 Mediated Chronic Inflammation
Circulation Research·2023
Nanoblades allow high-level genome editing in murine and human organoids
Molecular Therapy — Nucleic Acids·2023· 21 citedOpen Access
VEGF overexpressed mesoangioblasts enhance urethral and vaginal recovery following simulated vaginal birth in rats
Scientific Reports·2023· 3 citedOpen Access
<i>CTNS</i> mRNA as a potential treatment for nephropathic cystinosis
2023· 2 citedOpen Access
Data from HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development
2023Open Access
supplementary table S2 from HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development
2023Open Access
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Frequent Co-authors

Zeger Debyser(34), Jan De Rijck(16), Frauke Christ(13), Veerle Baekelandt(11), Chris Van den Haute(9), Sofie Vets(7), Jaan Toelen(7), Jonas Demeulemeester(6), Jelle Hendrix(6), Guy Bormans(6), Mathieu Bollen(5), Christophe M. Deroose(5), Hugo Ceulemans(4), Frederic D. Bushman(4), Rik Schrijvers(4), Anke Van der Perren(4), Willy Stalmans(3), Wannes Thys(3), Stéphane Emiliani(3), Richard Bénarous(3)