Jan De Rijck

Immunology and Microbiology · Life Sciences

31h-index3.0kcitations136works0.02yr avg
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Research Topics

HIV Research and Treatment(75), HIV/AIDS drug development and treatment(59), Virus-based gene therapy research(24), CRISPR and Genetic Engineering(15), Chronic Lymphocytic Leukemia Research(15)

Publications136 total

Data Supplement from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia
2023Open Access
Data from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia
2023Open Access
Data Supplement from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia
2023Open Access
Data Supplement from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia
2023Open Access
Data Supplement from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia
2023Open Access
Data from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia
2023Open Access
Data Supplement from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia
2023Open Access
Data Supplement from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia
2023Open Access
BET-Independent Murine Leukemia Virus Integration Is Retargeted <i>In Vivo</i> and Selects Distinct Genomic Elements for Lymphomagenesis
Microbiology Spectrum·2022· 6 citedOpen Access
BET-independent MLV integration is retargeted <i>in vivo</i> and selects distinct genomic elements for lymphomagenesis
2022Open Access
A ubiquitous disordered protein interaction module orchestrates transcription elongation
Science·2021· 68 citedOpen Access
Unlike its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival
Cells·2021· 12 citedOpen Access
Correction: Y-box-binding protein 1 supports the early and late steps of HIV replication
PLoS ONE·2020Open Access
Correction: LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs
PLoS Pathogens·2020Open Access
Correction to: HIV-1 IN/Pol recruits LEDGF/p75 into viral particles
Retrovirology·2020Open Access
Correction to: LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions
Retrovirology·2020· 1 citedOpen Access
PF219 THE LEDGF/P75 HOMOLOG HRP2 IS NOT IMPORTANT FOR THE INITIATION OF MLL‐REARRANGED LEUKEMIA
HemaSphere·2019Open Access
Y-box-binding protein 1 supports the early and late steps of HIV replication
PLoS ONE·2018· 17 citedOpen Access
Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation
Proceedings of the National Academy of Sciences·2018· 42 citedOpen Access
Withdrawal: Role of the PWWP domain of lens epithelium-derived growth factor (LEDGF)/p75 cofactor in lentiviral integration targeting
Journal of Biological Chemistry·2018Open Access
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Frequent Co-authors

Zeger Debyser(47), Rik Gijsbers(29), Frauke Christ(26), Jonas Demeulemeester(16), Sofie Vets(12), Sara El Ashkar(8), Kateřina Čermáková(8), Frederic D. Bushman(7), Rik Schrijvers(7), Jelle Hendrix(6), Linos Vandekerckhove(5), Nirav Malani(5), Caroline Weydert(5), Václav Veverka(5), Wannes Thys(4), Katrien Busschots(4), Keshet Ronen(4), Koen Bartholomeeusen(4), Siska Van Belle(4), Stéphane Emiliani(3)