Bansri Furia

PTC Therapeutics (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index1.1kcitations21works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

RNA modifications and cancer(10), Biochemical and Molecular Research(10), RNA Research and Splicing(7), Cancer, Hypoxia, and Metabolism(4), Neonatal Health and Biochemistry(4)

Publications21 total

Supplementary Excel file-1 from Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties
2023Open Access
Supplementary Excel file-1 from Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties
2023Open Access
Data from Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties
2023Open Access
Data from Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties
2023Open Access
Supplementary Figures S1-S7; Supplementary Tables S1-S7; and Supplementary Materials and Methods from Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties
2023Open Access
Supplementary Figures S1-S7; Supplementary Tables S1-S7; and Supplementary Materials and Methods from Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties
2023Open Access
CCDC 2163451: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
SAR studies toward discovery of emvododstat (PTC299), a potent dihydroorotate dehydrogenase (DHODH) inhibitor
European Journal of Medicinal Chemistry·2022· 3 citedOpen Access
Emvododstat, a Potent Dihydroorotate Dehydrogenase Inhibitor, Is Effective in Preclinical Models of Acute Myeloid Leukemia
Frontiers in Oncology·2022· 13 citedOpen Access
Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent
Molecular Cancer Therapeutics·2021· 21 citedOpen Access
Inhibition of De Novo Pyrimidine Nucleotide Synthesis By the Novel DHODH Inhibitor PTC299 Induces Differentiation and/or Death of AML Cells
Blood·2019· 5 cited
PS1004 PTC299 IS A NOVEL DHODH INHIBITOR FOR USE IN TREATMENT OF AML
HemaSphere·2019Open Access
Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties
Molecular Cancer Therapeutics·2018· 77 cited
Autosomal-Recessive Mutations in the tRNA Splicing Endonuclease Subunit TSEN15 Cause Pontocerebellar Hypoplasia and Progressive Microcephaly
The American Journal of Human Genetics·2016· 23 citedOpen Access
Autosomal-Recessive Mutations in the tRNA Splicing Endonuclease Subunit TSEN15 Cause Pontocerebellar Hypoplasia and Progressive Microcephaly
The American Journal of Human Genetics·2016· 59 citedOpen Access
<i>SMN2</i> splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
Science·2014· 517 cited
SMN2 Gene Splicing Modifiers Restore Lifespan and Motor Behavior in a Mouse Model of Spinal Muscular Atrophy.
2014
T.P.7 Small molecule compounds correct alternative splicing of the SMN2 gene and restore SMN protein expression and function
Neuromuscular Disorders·2012· 6 cited
G.P.2.17 An innovative and integrated approach to identify compounds that modulate SMN protein expression at the post-transcriptional level
Neuromuscular Disorders·2007
Identification of a Human Endonuclease Complex Reveals a Link between tRNA Splicing and Pre-mRNA 3′ End Formation
Cell·2004· 245 citedOpen Access
page 1 of 2Next →

Frequent Co-authors

Marla Weetall(16), Josephine Sheedy(13), Young‐Choon Moon(12), Joseph M. Colacino(12), Christopher R. Trotta(12), Ronald Kong(11), Stuart W. Peltz(11), Liangxian Cao(11), John Babiak(10), Neil G. Almstead(10), Nicole Risher(9), Tamil Arasu(9), Jiyuan Ma(8), Jason D. Graci(8), Wencheng Li(8), Jean Hedrick(8), Shirley Yeh(8), Hongyan Qi(8), Katherine Cintron(7), Charles Romfo(7)