Ulrike Gerdemann

Medicine · Health Sciences

23h-index3.8kcitations133works3.02yr avg
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Research Topics

CAR-T cell therapy research(71), Virus-based gene therapy research(43), Immune Cell Function and Interaction(29), Immunotherapy and Immune Responses(27), Cytomegalovirus and herpesvirus research(23)

Publications133 total

Refined Design of a CD117 Antibody-Drug Conjugate Safely and Effectively Conditions Non-Human Primates for Autologous Transplant-Based Gene Therapy
Transplantation and Cellular Therapy·2026
Feasibility of Post-Transplant Decitabine and G-CSF Maintenance in Children and Young Adults with Myeloid Malignancies: Interim Results from the More Trial
Transplantation and Cellular Therapy·2026
Multiomic Immune Profiling of Pediatric Transplant Recipients Identifies Cell States Associated with Vaccine Response
Clinical Journal of the American Society of Nephrology·2025Open Access
Refined design of a CD117 antibody-drug conjugate safely and effectively conditions non-human primates for autologous transplant-based gene therapy
Blood·2025
In Vivo correction of the sickle cell disease mutation in hematopoietic stem cells using RNA gene writers
Blood·2025Open Access
Organ-specific microenvironments drive divergent T cell evolution in acute Graft-Versus-Host Disease 3176
The Journal of Immunology·2025Open Access
Abstract A020-PR004: KAT6A and KAT6B are therapeutic targets to enhance the efficacy of differentiation therapy and GD2 immunotherapy in neuroblastoma
Cancer Research·2025
PTPN2-KO CAR-T Cells Demonstrate Enhanced Effector Function, CNS Infiltration, and Toxicity in a Non-Human Primate CAR-T Model
2025Open Access
KAT6A/B inhibition synergizes with retinoic acid and enhances the efficacy of GD2-targeted immunotherapy in neuroblastoma
2025Open Access
A single dose of a CD137 antibody–drug conjugate protects rhesus macaque allogeneic HCT recipients against acute GVHD
Blood·2025· 1 citedOpen Access
343 | A PILOT STUDY OF AXICABTAGENE CILOLEUCEL FOR THE TREATMENT OF RELAPSED/REFRACTORY PRIMARY AND SECONDARY CENTRAL NERVOUS SYSTEM LYMPHOMA
Hematological Oncology·2025Open Access
Using single-cell transcriptomics to reveal CD226 upregulation and enhancement of CD19-CAR-T function in the inhibitory CNS microenvironment of refractory CNS lymphoma.
Journal of Clinical Oncology·2025
Precision Editing of Cyclophilin A Generates Cyclosporine and Voclosporin Resistant Cellular Therapies
2025Open Access
Abstract 2601: KAT6A and B inhibition increases efficacy of differentiation and GD2 targeting immunotherapy in neuroblastoma
Cancer Research·2025
Personalized Immune Profiling in Pediatric Transplant Recipients: Linking Atypical B Cells to Vaccine Response
2025Open Access
Abstract A020: Treatment of neuroblastoma with retinoic acid plus a KAT6A/B inhibitor induces sustained growth arrest and increases GD2 expression as a target for immunotherapy
Cancer Research·2025
Chronic Graft-Versus-Host Disease Incidence and Long-Term Outcomes for Children and AYA Patients Transplanted at a Large Single Center.
Transplantation and Cellular Therapy·2025
Organ-specific microenvironments drive divergent T cell evolution in acute graft-versus-host disease
Science Translational Medicine·2025· 6 citedOpen Access
245 Leveraging RNA gene writer and lipid nanoparticle delivery to engineer T cells <i>in vivo</i> using all-RNA compositions
Regular and Young Investigator Award Abstracts·2024Open Access
Human OX40L–CAR-T <sub>regs</sub> target activated antigen-presenting cells and control T cell alloreactivity
Science Translational Medicine·2024· 25 citedOpen Access
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Frequent Co-authors

Ann M. Leen(25), Cliona M. Rooney(20), Helen E. Heslop(15), Malcolm K. Brenner(13), Juan F. Vera(12), Leslie S. Kean(12), Usha L. Katari(8), Catherine M. Bollard(8), Victor Tkachev(8), James J. Kaminski(7), Stephen Gottschalk(7), Adrian P. Gee(6), Connor McGuckin(6), Bruce R. Blazar(6), Xianliang Rui(6), Lorenzo Cagnin(6), W. Nicholas Haining(5), Αναστασία Παπαδοπούλου(5), Carlos A. Ramos(5), Kathleen B. Yates(4)