Zhiya Yu

National Institutes of Health — United States

Medicine · Health Sciences

67h-index22.3kcitations300works3.82yr avg
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Research Topics

CAR-T cell therapy research(197), Immunotherapy and Immune Responses(110), Cancer Immunotherapy and Biomarkers(79), Immune Cell Function and Interaction(64), Virus-based gene therapy research(41)

Publications298 total

Transcriptome analysis reveals physiological responses in liver tissues of Epinephelus cyanopodus under acute hypoxic stress
Frontiers in Physiology·2025Open Access
Selective expansion of T-cell receptor engineered T cells with increased stem-like phenotypes using neoantigen stimulation
Journal for ImmunoTherapy of Cancer·2025Open Access
T cell receptors targeting mutant NPM1 for adoptive cell therapy in acute myeloid leukemia
Blood·2025
375  <i>KLF2</i> -overexpression imparts stemness onto dysfunctional neoantigen-reactive human tumor-infiltrating lymphocytes
Regular and Young Investigator Award Abstracts·2025Open Access
Molecular characterization and expression analysis of hypoxia inducible factor-1α during hypoxic stress in speckled blue grouper (Epinephelus cyanopodus)
Frontiers in Marine Science·2025· 1 citedOpen Access
Rapid enrichment of progenitor exhausted neoantigen-specific CD8 T cells from peripheral blood
2025· 3 citedOpen Access
Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
Cell·2025· 15 cited
367 CD8 coreceptor dependence in HLA class I neoantigen-targeted TCR therapy
Regular and Young Investigator Award Abstracts·2024Open Access
Identification and structural characterization of a mutant KRAS‐G12V specific TCR restricted by HLA‐A3
European Journal of Immunology·2024· 3 citedOpen Access
Author response for "Identification and structural characterization of a mutant KRAS‐G12V specific TCR restricted by HLA‐A3"
2024
Author response for "Identification and structural characterization of a mutant KRAS‐G12V specific TCR restricted by HLA‐A3"
2024· 1 cited
Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes
Journal for ImmunoTherapy of Cancer·2024· 27 citedOpen Access
Identification and Structural Characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3
2024Open Access
369 Concurrent neoantigen vaccination enhances the antitumor effect of dysfunctional T cells during cell therapy
Regular and Young Investigator Award Abstracts·2023Open Access
P2.05-10 The Power for PD-L1 Expression to Predict Immune Checkpoint Blockade Outcomes is Determined by Tumor Transcriptome
Journal of Thoracic Oncology·2023· 1 citedOpen Access
Identification of neoepitope reactive T-cell receptors guided by HLA-A*03:01 and HLA-A*11:01 immunopeptidomics
Journal for ImmunoTherapy of Cancer·2023· 8 citedOpen Access
Data from Identification and Validation of T-cell Receptors Targeting &lt;i&gt;RAS&lt;/i&gt; Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy
2023Open Access
Supplementary Data from Identification and Validation of T-cell Receptors Targeting &lt;i&gt;RAS&lt;/i&gt; Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy
2023Open Access
Supplementary Data from Identification and Validation of T-cell Receptors Targeting &lt;i&gt;RAS&lt;/i&gt; Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy
2023Open Access
Supplementary Data from Identification and Validation of T-cell Receptors Targeting &lt;i&gt;RAS&lt;/i&gt; Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy
2023Open Access
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Frequent Co-authors

Nicholas P. Restifo(43), Steven A. Rosenberg(29), Luca Gattinoni(24), Douglas C. Palmer(22), Christopher A. Klebanoff(17), Pawel Muranski(15), Madhusudhanan Sukumar(11), Rahul Roychoudhuri(11), Yun Ji(10), Robert Eil(9), Chrystal M. Paulos(7), Ena Wang(7), Francesco M. Marincola(7), Claudia Wrzesinski(7), Christian S. Hinrichs(7), David Clever(7), Paul F. Robbins(7), Richard A. Morgan(7), Sid P. Kerkar(7), Tori N. Yamamoto(6)