Luca Gattinoni

University Hospital Regensburg — Germany

Medicine · Health Sciences

71h-index25.3kcitations227works20.12yr avg
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Research Topics

CAR-T cell therapy research(122), Immune Cell Function and Interaction(101), Immunotherapy and Immune Responses(82), T-cell and B-cell Immunology(66), Cancer Immunotherapy and Biomarkers(44)

Publications227 total

Multi-faceted influence of immunomodulatory metabolites on CAR-T cell therapy
Blood·2025Open Access
In Vivo clonal dynamics of alloreactive CAR T cells reveal mechanisms limiting gvhd risk following allogeneic CAR T cell therapy
Blood·2025Open Access
Targeting organelle function in T cells for cancer immunotherapy
Nature reviews. Immunology·2025
CAR T cells re-directed by a rationally designed human peptide tag demonstrate efficacy in preclinical models
Cytotherapy·2025· 1 citedOpen Access
Restoring the supply lines: removing roadblocks to fatty acid uptake enhances T cell-driven cancer fight
Signal Transduction and Targeted Therapy·2025· 1 citedOpen Access
Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy
Cell·2024· 147 citedOpen Access
NaCl enhances CD8+ T cell effector functions in cancer immunotherapy
Nature Immunology·2024· 41 cited
LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness
Nature Communications·2024· 12 citedOpen Access
LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling
Signal Transduction and Targeted Therapy·2024· 14 citedOpen Access
Nanowires engineer naive T cells for immunotherapy
Nature Nanotechnology·2024· 1 cited
Synthetic soldiers: Turning T cells into immortal warriors
The Journal of Experimental Medicine·2024· 4 citedOpen Access
Rapid Screening of CAR T Cell Functional Improvement Strategies by Highly Multiplexed Single-Cell Secretomics
Methods in molecular biology·2023
Dataset #1 related to article "NaCl enhances CD8+ T-cell effector functions in cancer immunotherapy"
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Dataset #1 related to article "NaCl enhances CD8+ T-cell effector functions in cancer immunotherapy"
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Dataset related to article "Potent CD8+ T cell effector functions induced by NaCl in cancer immunotherapy"
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Releasing the brake: CTLA-4 loss turbocharges CAR T cells
Immunity·2023· 6 citedOpen Access
Independent Prognostic and Predictive Role of Interstitial Macrophages in Kidney Biopsies of IgA Nephropathy Patients
Journal of Personalized Medicine·2023· 1 citedOpen Access
Supplementary Figures 1 - 12 and Tables 1 - 11 from Type I Cytokines Synergize with Oncogene Inhibition to Induce Tumor Growth Arrest
2023Open Access
Supplementary Materials and Methods from Type I Cytokines Synergize with Oncogene Inhibition to Induce Tumor Growth Arrest
2023Open Access
Data from Type I Cytokines Synergize with Oncogene Inhibition to Induce Tumor Growth Arrest
2023Open Access
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Frequent Co-authors

Nicholas P. Restifo(39), Douglas C. Palmer(24), Zhiya Yu(21), Christopher A. Klebanoff(21), Yun Ji(19), Steven A. Rosenberg(16), Pawel Muranski(15), Rahul Roychoudhuri(11), Madhusudhanan Sukumar(10), David Clever(8), Chrystal M. Paulos(7), Ena Wang(7), Francesco M. Marincola(7), Christian S. Hinrichs(7), Joseph G. Crompton(7), Zachary A. Borman(7), Robert Eil(7), Paul A. Antony(6), Claudia Wrzesinski(6), Warren J. Leonard(6)