Claudia Wrzesinski

Center for Biologics Evaluation and Research — United States

Immunology and Microbiology · Life Sciences

17h-index5.2kcitations26works1.02yr avg
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Research Topics

Immunotherapy and Immune Responses(15), Immune Cell Function and Interaction(14), CAR-T cell therapy research(13), T-cell and B-cell Immunology(7), Hematopoietic Stem Cell Transplantation(3)

Publications26 total

Contributors
Elsevier eBooks·2024
Potential value of animal microphysiological systems
ALTEX·2024· 3 citedOpen Access
Animal Models for Infectious Disease Vaccine Development
Elsevier eBooks·2024
COVID-19 Therapeutics and Vaccines: A Race to Save Lives
Toxicological Sciences·2021· 13 citedOpen Access
Toll-like receptor agonist therapy augments the antitumor activity of adoptively transferred CD8+ T cells without host preconditioning
The Journal of Immunology·2016
A novel method for deriving thresholds of toxicological concern for vaccine constituents
Toxicology Mechanisms and Methods·2016· 6 cited
Toll-like receptor agonist therapy can profoundly augment the antitumor activity of adoptively transferred CD8+ T cells without host preconditioning
Journal for ImmunoTherapy of Cancer·2016· 27 citedOpen Access
miR-155 augments CD8 <sup>+</sup> T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γ <sub>c</sub> cytokines
Proceedings of the National Academy of Sciences·2014· 114 citedOpen Access
Increased Intensity Lymphodepletion Enhances Tumor Treatment Efficacy of Adoptively Transferred Tumor-specific T Cells
Journal of Immunotherapy·2009· 274 cited
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
Nature Medicine·2009· 988 citedOpen Access
Type 17 CD8+ T cells display enhanced antitumor immunity
Blood·2009· 225 citedOpen Access
Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers
Blood·2008· 40 citedOpen Access
Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity
Proceedings of the National Academy of Sciences·2008· 126 citedOpen Access
Tumor-specific Th17-polarized cells eradicate large established melanoma
Blood·2008· 819 citedOpen Access
Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling
Journal of Clinical Investigation·2007· 19 citedOpen Access
Toll-like Receptors in Tumor Immunotherapy
Clinical Cancer Research·2007· 122 citedOpen Access
Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling
Journal of Clinical Investigation·2007· 578 citedOpen Access
Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8+ T cells
Journal of Clinical Investigation·2007· 198 citedOpen Access
Increased intensity lymphodepletion and adoptive immunotherapy—how far can we go?
Nature Clinical Practice Oncology·2006· 345 citedOpen Access
Partly MHC Matched Allogeneic Tumor Specific T Cells Mediate Tumor Regression without Inducing GVHD in Immunosuppressed Host.
Blood·2006
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Frequent Co-authors

Nicholas P. Restifo(20), Luca Gattinoni(15), Douglas C. Palmer(15), Chrystal M. Paulos(14), Zhiya Yu(12), Steven A. Rosenberg(10), Pawel Muranski(10), Andrew Kaiser(10), Christian S. Hinrichs(8), Andrea Boni(7), Lydie Cassard(7), Christopher A. Klebanoff(5), Paul A. Antony(5), Steven E. Finkelstein(3), Leroy N. Hwang(2), Charles D. Surh(2), Yun Ji(2), Keith Kerstann(2), Marcello Chieppa(2), Luis Sánchez-Pérez(2)