Emrah Ilker Ozay

Sarepta Therapeutics (United States) — United States

Medicine · Health Sciences

10h-index411citations20works0.02yr avg
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Research Topics

CAR-T cell therapy research(12), RNA Interference and Gene Delivery(6), Immunotherapy and Immune Responses(5), Monoclonal and Polyclonal Antibodies Research(5), Viral Infectious Diseases and Gene Expression in Insects(3)

Publications20 total

Editorial: Treating solid organ diseases with innovative chimeric-antigen receptor T-cells: current indications, progress, limitations and potential strategies
Frontiers in Immunology·2024Open Access
Abstract 2853: Co-delivery of antigen-encoding mRNA and signal 2/3 mRNAs to PBMCs by Cell Squeeze® technology generates SQZ™ eAPCs that prime CD8+T cells in a humanized mouse model
Cancer Research·2022
Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8+ T Cell Responses with Antitumor Activity
The Journal of Immunology·2022· 21 citedOpen Access
156 RBC-derived, activating antigen carriers (SQZ AACs) prime potent T cell responses and drive tumor regression in vivo
Regular and Young Investigator Award Abstracts·2021· 1 citedOpen Access
211 SQZ™ eAPCs generated from PBMCs by delivery of multiple mRNAs encoding for antigens, costimulatory proteins, and engineered cytokines
Regular and Young Investigator Award Abstracts·2021Open Access
Abstract 1525: Enhancing potency of antigen presenting cells via signal 2/3 mRNA engineering through Cell Squeeze® technology
Cancer Research·2021· 1 cited
Abstract 1523: Cell Squeeze® delivery of antigen-encoding mRNA enables human PBMCs to drive antigen-specific CD8+ T cell responses for diverse clinical applications
Cancer Research·2021
Defining and Manipulating the Function of Protein Kinase C-theta in Graft versus Host Responses
Scholarworks (University of Massachusetts Amherst)·2021Open Access
170 Microfluidics cell squeezing enables potent cellular vaccines in murine models through direct cytosolic loading and direct CD8 T cell priming
Regular and Young Investigator Award Abstracts·2020· 2 citedOpen Access
Anti-pPKCθ (T538) Delivery via Cell Penetrating Peptide Mimics as a Novel Treatment of Aplastic Anemia
The Journal of the American Medical Association (JAMA) Network (American Medical Association)·2020Open Access
Protein Kinase C Theta Modulates PCMT1 through hnRNPL to Regulate FOXP3 Stability in Regulatory T Cells
Molecular Therapy·2020· 21 citedOpen Access
Cell-Penetrating Anti-Protein Kinase C Theta Antibodies Act Intracellularly to Generate Stable, Highly Suppressive Regulatory T Cells
Molecular Therapy·2020· 19 citedOpen Access
Alpha-1 Antitrypsin-Expressing Mesenchymal Stromal Cells Confer a Long-Term Survival Benefit in a Mouse Model of Lethal GvHD
Molecular Therapy·2019· 14 citedOpen Access
Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease
Stem Cell Research·2019· 52 citedOpen Access
Rotenone Treatment Reveals a Role for Electron Transport Complex I in the Subcellular Localization of Key Transcriptional Regulators During T Helper Cell Differentiation
Frontiers in Immunology·2018· 25 citedOpen Access
A common antimicrobial additive increases colonic inflammation and colitis-associated colon tumorigenesis in mice
Science Translational Medicine·2018· 152 citedOpen Access
Effects of Consumer Antimicrobials Benzalkonium Chloride, Benzethonium Chloride, and Chloroxylenol on Colonic Inflammation and Colitis-Associated Colon Tumorigenesis in Mice
Toxicological Sciences·2018· 27 citedOpen Access
Sequence segregation improves non-covalent protein delivery
Journal of Controlled Release·2017· 43 cited
Intracellular Delivery of Anti-pPKCθ (Thr538) via Protein Transduction Domain Mimics for Immunomodulation
Molecular Therapy·2016· 33 citedOpen Access
Intracellular delivery of anti-pPKCθ (T538) via protein transduction domain mimics for T cell immunomodulation
The Journal of Immunology·2016

Frequent Co-authors

Lisa M. Minter(10), Gregory N. Tew(8), Howard Bernstein(7), Scott Loughhead(7), Joe Torres(5), Barbara A. Osborne(5), Armon Sharei(5), Sudarvili Shanthalingam(4), Heather L. Sherman(4), Carolyne K. Smith(4), Kelly Volk(4), Katarina Blagović(4), Pablo Umaña(4), Michael F. Maloney(4), Jyothi Vijayaraghavan(3), Gabriela González‐Pérez(3), Christian Yee(3), Amy Merino(3), Christine Trumpfheller(3), Katherine J. Seidl(3)