Janete Cunha‐Santos

Neuroscience · Life Sciences

8h-index329citations13works2.02yr avg
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Research Topics

Genetic Neurodegenerative Diseases(10), Mitochondrial Function and Pathology(4), Autophagy in Disease and Therapy(4), Sirtuins and Resveratrol in Medicine(3), Endoplasmic Reticulum Stress and Disease(2)

Publications13 total

Long-term efficacy and safety of alemtuzumab in participants with highly active MS: TOPAZ clinical trial and interim analysis of TREAT-MS real-world study
Therapeutic Advances in Neurological Disorders·2025· 2 citedOpen Access
Nuclear aging in polyglutamine-induced neurodegeneration
2023· 1 citedOpen Access
SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway
International Journal of Molecular Sciences·2022· 16 citedOpen Access
Identification of the calpain‐generated toxic fragment of ataxin‐3 protein provides new avenues for therapy of Machado–Joseph disease| Spinocerebellar ataxia type 3
Neuropathology and Applied Neurobiology·2021· 8 cited
Trehalose alleviates the phenotype of Machado–Joseph disease mouse models
Journal of Translational Medicine·2020· 33 citedOpen Access
Autophagy activation induced by let-7 microRNA overexpression counteracts disease phenotype in Machado-Joseph disease mouse models
Frontiers in Cellular Neuroscience·2019· 1 citedOpen Access
Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis
Advances in experimental medicine and biology·2018· 22 cited
Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese mice
Biochimica et Biophysica Acta (BBA) - General Subjects·2017· 25 citedOpen Access
Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease
Molecular Therapy·2017· 63 citedOpen Access
Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway
Nature Communications·2016· 107 citedOpen Access
Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway
RePEc: Research Papers in Economics·2016Open Access
Neuropeptide Y alleviates Machado–Joseph disease
Neuropeptides·2016
Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado–Joseph disease
Human Molecular Genetics·2015· 51 citedOpen Access

Frequent Co-authors

Luís Pereira de Almeida(11), Cláudia Cavadas(9), Joana Duarte‐Neves(7), Vítor Carmona(6), Ana Teresa Simões(5), Nélio Gonçalves(3), Leonard Guarente(2), Isabel Onofre(2), Wilfred F.A. den Dunnen(2), Hirokazu Hirai(2), Sebastian Kügler(2), Magda M. Santana(2), Clévio Nóbrega(2), Helena Leal(2), Sónia Duarte(2), Ana Vasconcelos‐Ferreira(2), Dina Pereira(2), Udaya Geetha Vijayakumar(1), Beverly L. Davidson(1), Susana Paixão(1)