Joshua D. Webster

Biochemistry, Genetics and Molecular Biology · Life Sciences

47h-index9.8kcitations170works4.82yr avg
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Research Topics

Cell death mechanisms and regulation(21), Cancer Cells and Metastasis(21), Veterinary Oncology Research(16), RNA modifications and cancer(16), Chemical Reactions and Isotopes(16)

Publications170 total

cFLIP suppresses caspase-1- and MLKL-independent perinatal lethality driven by auto-processing impaired caspase-8 D387A
Cell Death and Differentiation·2025Open Access
Author Correction: Activity of caspase-8 determines plasticity between cell death pathways
Nature·2025Open Access
Author Correction: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis
Nature·2025Open Access
Molecular subtypes of hepatocellular carcinoma linked to liver cell lineages and clinical outcomes of combination immunotherapy
Cell Reports Medicine·2025Open Access
Author Correction: Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury
Nature·2025Open Access
Dissecting NOD2 inflammatory signaling in a Blau syndrome model 9380
The Journal of Immunology·2025Open Access
Discovery of Clinical Candidate GDC-8264, a Novel, Potent and Selective RIP1 Inhibitor for Amelioration of Tissue Damage and the Treatment of Inflammatory Diseases
Journal of Medicinal Chemistry·2025
IRF2 degradation tunes the innate immune response
2025Open Access
Reviewer-in-training: A mentoring opportunity in the peer review process
Veterinary Pathology·2025Open Access
Reporting guidelines for manuscripts that use artificial intelligence–based automated image analysis in <i>Veterinary Pathology</i>
Veterinary Pathology·2025
199 Effectiveness of hypothermic machine perfusion and static cold storage as delivery methods of a novel RIPK1 inhibitor into pig kidneys and its effects on ischaemia-reperfusion injury
British journal of surgery·2025Open Access
Abstract PR002: T cell engager therapy affects the spatial distribution and phenotype of T cells in the tumor microenvironment
Cancer Immunology Research·2025· 1 cited
Impairment of DET1 causes neurological defects and lethality in mice and humans
Proceedings of the National Academy of Sciences·2025· 3 citedOpen Access
Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade
Nature Communications·2024· 23 citedOpen Access
RIP1 inhibition protects retinal ganglion cells in glaucoma models of ocular injury
Cell Death and Differentiation·2024· 8 citedOpen Access
Voxel-based analysis of renal fibrosis with diffusion MRI in mouse models
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2024
Diffusion tensor MRI is sensitive to fibrotic injury in a mouse model of oxalate-induced chronic kidney disease
American Journal of Physiology-Renal Physiology·2024· 1 cited
N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation
Immunity·2024· 23 citedOpen Access
ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1
Cell Death and Differentiation·2024· 24 citedOpen Access
Caspase cleavage of RIPK3 after Asp333 is dispensable for mouse embryogenesis
Cell Death and Differentiation·2024· 11 citedOpen Access
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Frequent Co-authors

Kim Newton(23), Vishva M. Dixit(19), Merone Roose‐Girma(14), Debra L. Dugger(13), Matti Kiupel(11), Wyne P. Lee(9), Zora Modrušan(9), Rohit Reja(8), Domagoj Vucic(8), Allie Maltzman(7), Donald S. Kirkpatrick(7), Vilma Yuzbasiyan‐Gurkan(6), Nobuhiko Kayagaki(5), Brent S. McKenzie(5), Katherine E. Wickliffe(5), László G. Kömüves(5), Jason DeVoss(5), Søren Warming(4), Benjamin Haley(4), Jinfeng Liu(4)