Raymond G. Nanni

Advanced Pharma — United States

Immunology and Microbiology · Life Sciences

12h-index2.6kcitations18works0.02yr avg
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Research Topics

HIV Research and Treatment(8), HIV/AIDS drug development and treatment(8), Biochemical and Molecular Research(4), DNA and Nucleic Acid Chemistry(3), Crystallography and molecular interactions(3)

Publications18 total

Insights into DNA Polymerization Mechanisms from Structure and Function Analysis of HIV-1 Reverse Transcriptase
Biochemistry·1995· 163 cited
Locations of Anti-AIDS Drug Binding Sites and Resistance Mutations in the Three-dimensional Structure of HIV-1 Reverse Transcriptase
Journal of Molecular Biology·1994· 518 cited
Buried surface analysis of HIV‐1 reverse transcriptase p66/p51 heterodimer and its interaction with dsDNA template/primer
Journal of Molecular Recognition·1994· 30 cited
Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.
Proceedings of the National Academy of Sciences·1994· 148 citedOpen Access
Recent results and new hardware developments for protein crystal growth in microgravity
Journal of Crystal Growth·1994· 65 cited
Structure of HIV-1 reverse transcriptase/dsDNA/Fab complex: protein-DNA interactions and structure of the polymerase active site
Acta Crystallographica Section A Foundations of Crystallography·1993Open Access
Review of HIV-1 reverse transcriptase three-dimensional structure: Implications for drug design
Perspectives in Drug Discovery and Design·1993· 133 cited
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.
Proceedings of the National Academy of Sciences·1993· 1.1k citedOpen Access
Structure Determination of Antiviral Compound SCH 38057 Complexed with Human Rhinovirus 14
Journal of Molecular Biology·1993· 43 cited
Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations
Nature·1992· 187 cited
Electrostatic properties of 1-methyluracil from diffraction data
Acta Crystallographica Section B Structural Science·1992· 33 cited
Electrostatic properties of 1-methyluracil from diffraction data
University of Twente Research Information·1992
Crystals of a ternary complex of human immunodeficiency virus type 1 reverse transcriptase with a monoclonal antibody Fab fragment and double-stranded DNA diffract x-rays to 3.5-A resolution.
Proceedings of the National Academy of Sciences·1991· 62 citedOpen Access
Molecular Distortions in Crystals.
PhDT·1988
ChemInform Abstract: Neutron Diffraction Analysis at 15 K and ab initio Molecular Orbital Calculations for α‐Cyanoacetohydrazide: a Crystal Structure with a High Energy Conformer
ChemInform·1987
Neutron diffraction analysis at 15 K and ab initio molecular orbital calculations for α-cyanoacetohydrazide: A crystal structure with a high energy conformer
Journal of Molecular Structure·1986· 8 cited
Neutron diffraction at 15 K and <i>ab initio</i> molecular-orbital studies of the molecular structure of carbonohydrazide (carbohydrazide)
Acta Crystallographica Section B Structural Science·1985· 9 cited
The crystal structure of anhydrous α,α-trehalose at −150°
Carbohydrate Research·1985· 99 cited

Frequent Co-authors

Alfredo Jacobo‐Molina(11), Eddy Arnold(11), Jianping Ding(6), Chris Tantillo(6), Arthur D. Clark(5), Stephen H. Hughes(5), Roger Williams(4), Greg Kamer(3), Andrea L. Ferris(3), S H Hughes(3), G. A. Jeffrey(3), J. R. Ruble(3), Lu Xiao(2), Patricia Clark(2), Amnon Hizi(2), Paul L. Boyer(2), Xiaode Lu(2), Wim T. Klooster(2), R. K. McMullan(2), Jianping Ding(1)